| 抗疲劳中药刺五加中1个新倍半萜 |
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| 引用本文： | 于亮,张军武,石新燕,刘昭,孙涛,梁文娟.抗疲劳中药刺五加中1个新倍半萜[J].中草药,2018,49(11):2508-2511. |
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| 作者姓名： | 于亮 张军武 石新燕 刘昭 孙涛 梁文娟 |
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| 作者单位： | 陕西中医药大学体育部;陕西中医药大学药学院;云南农业大学食品科技学院 |
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| 基金项目： | 国家自然科学基金青年基金资助项目（31600279） |
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| 摘 要： | 目的研究中药刺五加Acanthopanax senticosus的抗疲劳活性成分。方法采用硅胶、Sephadex LH-20、MCI gel CHP-20P、ODS等多种色谱技术分离纯化,通过质谱及核磁共振等数据对化合物进行结构鉴定;并采用ABTS法研究其体外清除自由基活性。结果从刺五加甲醇提取物中分离得到1个倍半萜类化合物7α(H)-桉烷-4α,5β,11,12-四醇-3-酮(1),该化合物自由基清除的半数清除浓度为(43.1±1.2)μg/m L。结论化合物1为1个新的eudesmane型倍半萜,命名为刺五加醇A;也是首次从五加科植物中分离得到此类化合物。
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| 关 键 词： | 刺五加 刺五加醇A 抗疲劳 倍半萜 自由基清除 |
| 收稿时间： | 2017/12/18 0:00:00 |
A new antifatigue eudesmane sesquiterpenoid from Acanthopanax senticosus |
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| YU Liang,ZHANG Jun-wu,SHI Xin-yan,LIU Zhao,SUN Tao and LIANG Wen-juan.A new antifatigue eudesmane sesquiterpenoid from Acanthopanax senticosus[J].Chinese Traditional and Herbal Drugs,2018,49(11):2508-2511. |
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| Authors: | YU Liang ZHANG Jun-wu SHI Xin-yan LIU Zhao SUN Tao and LIANG Wen-juan |
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| Institution: | Department of Physical Education, Shaanxi University of Chinese Medicine, Xi''an 712046, China,School of Pharmacy, Shaanxi University of Chinese Medicine, Xi''an 712046, China,Department of Physical Education, Shaanxi University of Chinese Medicine, Xi''an 712046, China,Department of Physical Education, Shaanxi University of Chinese Medicine, Xi''an 712046, China,School of Pharmacy, Shaanxi University of Chinese Medicine, Xi''an 712046, China and College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China |
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| Abstract: | |
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| Keywords: | Acanthopanax senticosus(Ruper et Maxim ) Maxim senticosol A anti-fatigue sesquiterpenoid free radical scavenging activity |
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