| 多孔菌科真菌中羊毛甾烷型三萜类成分及其药理作用研究进展 |
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| 引用本文： | 包海鹰,史帧婷,冯爽.多孔菌科真菌中羊毛甾烷型三萜类成分及其药理作用研究进展[J].中草药,2018,49(9):2172-2187. |
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| 作者姓名： | 包海鹰 史帧婷 冯爽 |
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| 作者单位： | 吉林农业大学中药材学院;吉林农业大学食药用菌教育部工程研究中心 |
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| 基金项目： | 国家自然科学基金资助项目（31270088） |
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| 摘 要： | 羊毛甾烷型三萜是四环三萜类化合物,是多孔菌科真菌中含量较为丰富的一类次级代谢产物。羊毛甾烷型三萜类化合物可以划分为A、B、C、D、E 5种主要骨架构型,具有抗肿瘤、抗炎、抗菌等药理活性。通过查阅国内外文献,对多孔菌科20多种真菌中分离出的161种羊毛甾烷型三萜类成分及药理作用研究进展进行了综述,为羊毛甾烷型三萜类成分的研究及多孔菌科真菌药用资源的合理应用与开发提供参考。
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| 关 键 词： | 真菌 多孔菌科 四环三萜 羊毛甾烷型三萜 抗肿瘤活性 抗炎活性 抗菌活性 |
| 收稿时间： | 2017/10/12 0:00:00 |
Research progress on lanostane-type triterpenoids in fungi of Polyporaceae and their pharmacological activities |
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| BAO Hai-ying,SHI Zhen-ting and FENG Shuang.Research progress on lanostane-type triterpenoids in fungi of Polyporaceae and their pharmacological activities[J].Chinese Traditional and Herbal Drugs,2018,49(9):2172-2187. |
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| Authors: | BAO Hai-ying SHI Zhen-ting and FENG Shuang |
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| Institution: | College of Chinese Medicine Material, Jilin Agricultural University, Changchun 130118, China;Engineering Research Center of Chinese Ministry of Education for Edible and Medicinal Fungi, Jilin Agricultural University, Changchun 130118, China,College of Chinese Medicine Material, Jilin Agricultural University, Changchun 130118, China;Engineering Research Center of Chinese Ministry of Education for Edible and Medicinal Fungi, Jilin Agricultural University, Changchun 130118, China and College of Chinese Medicine Material, Jilin Agricultural University, Changchun 130118, China |
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| Abstract: | Lanostane-type triterpenoid is a kind of tetracyclic triterpene compound, which belongs to secondary metabolics in fungi of Polyporaceae with abundant content.In the paper, combined with the domestic and foreign literature, the pharmacological activities on the 161 kinds of lanostane-type triterpenoids isolated from more than 20 species of Polyporaceae fungi are summarized.The compounds are divided into A, B, C, D, and E five kinds of main skeleton configurations.Their pharmacological activity researches are mainly concentrated in antitumor, anti-inflammatory, antibacterial and so on.The paper provides reference value for rational use and development of the medicinal resources of the fungi of Polyporaceae and their lanostane-type triterpenoids. |
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| Keywords: | fungi Polyporaceae tetracyclic triterpene lanostane-type triterpenoids antitumor activity anti-inflammatory activity antibacterial activity |
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