| 知母产地加工与饮片炮制一体化工艺研究 |
| |
| 引用本文： | 黄琪,贾鹏晖,吴德玲,金传山,许凤清,朱月健,李保明.知母产地加工与饮片炮制一体化工艺研究[J].中草药,2018,49(20):4760-4766. |
| |
| 作者姓名： | 黄琪 贾鹏晖 吴德玲 金传山 许凤清 朱月健 李保明 |
| |
| 作者单位： | 安徽中医药大学药学院;安徽省现代中药重点实验室;中药饮片制造新技术安徽省重点实验室;安徽济人药业有限公司 |
| |
| 基金项目： | 2015年度中医药行业科研专项项目（201507002-18）；安徽省高校科研创新平台团队（中药饮片产地加工与炮制一体化关键技术研究创新团队）建设项目（2015TD035）；国家中药标准化建设项目：白芷等5种中药饮片标准化建设（ZYBZH-Y-AH-02） |
| |
| 摘 要： | 目的优选知母Anemarrhenae Rhizoma产地加工与饮片炮制一体化工艺,为实现知母产地加工与饮片炮制一体化提供科学依据。方法采用单因素实验结合正交试验法对一体化加工工艺中鲜药的烘制温度、切制时药材含水量、切片厚度、饮片烘干温度4个影响因素进行考察,以知母中指标性成分知母皂苷B-Ⅱ、芒果苷含量及饮片外观性状为考察指标,采用综合评分法进行评价,优选知母产地加工工艺。以酵母致热大鼠模型体温变化为指标,比较2种工艺所得饮片的解热作用;以链脲佐菌素(STZ)致糖尿病大鼠模型的血糖值、胰岛素含量、糖化血清蛋白含量为指标,比较2种工艺所得饮片的降糖作用。结果知母于50℃条件烘制11 h(药材含水量45%～50%),于滚筒中撞去毛,脱毛时间30 min,切4 mm厚片,于50℃条件下烘干为最佳加工工艺;一体化工艺饮片指标性成分含量及降糖作用与《中国药典》2015年版传统工艺饮片相比无显著性差异,解热作用略优于传统饮片。结论本实验所优选的知母产地加工与饮片炮制一体化工艺切实可行,适合产业化生产。
|
| 关 键 词： | 知母 正交试验 产地加工与炮制一体化 解热 降糖 知母皂苷B-II 芒果苷 |
| 收稿时间： | 2018/3/14 0:00:00 |
Technology of combining field processing and crude drug processing of Anemarrhenae Rhizoma |
| |
| HUANG Qi,JIA Peng-hui,WU De-ling,JIN Chuan-shan,XU Feng-qing,ZHU Yue-jian and LI Bao-ming.Technology of combining field processing and crude drug processing of Anemarrhenae Rhizoma[J].Chinese Traditional and Herbal Drugs,2018,49(20):4760-4766. |
| |
| Authors: | HUANG Qi JIA Peng-hui WU De-ling JIN Chuan-shan XU Feng-qing ZHU Yue-jian and LI Bao-ming |
| |
| Institution: | College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China;Anhui Key Laboratory of Modern Chinese Medicine, Hefei 230012, China;Anhui Province Key Laboratory of Traditional Chinese Medicine Decoction Pieces of New Manufacturing Technology, Bozhou 236800, China,College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China,College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China;Anhui Key Laboratory of Modern Chinese Medicine, Hefei 230012, China;Anhui Province Key Laboratory of Traditional Chinese Medicine Decoction Pieces of New Manufacturing Technology, Bozhou 236800, China,College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China;Anhui Key Laboratory of Modern Chinese Medicine, Hefei 230012, China;Anhui Province Key Laboratory of Traditional Chinese Medicine Decoction Pieces of New Manufacturing Technology, Bozhou 236800, China,College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China;Anhui Key Laboratory of Modern Chinese Medicine, Hefei 230012, China;Anhui Province Key Laboratory of Traditional Chinese Medicine Decoction Pieces of New Manufacturing Technology, Bozhou 236800, China,AnHui Jiren Pharmaceutical Group, Bozhou 236800, China and Anhui Province Key Laboratory of Traditional Chinese Medicine Decoction Pieces of New Manufacturing Technology, Bozhou 236800, China |
| |
| Abstract: | |
| |
| Keywords: | |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中草药》浏览原始摘要信息 |
| 点击此处可从《中草药》下载免费的PDF全文 |
|
