台州地区汉族支气管哮喘控制水平与抑郁相关性研究

目的探讨台州地区部分汉族支气管哮喘(简称哮喘)患者的哮喘控制水平、肺功能与抑郁情绪存在的相关性,分析哮喘患者抑郁发生的可能原因。方法选择我院呼吸科门诊及住院哮喘患者126例为实验组,同时选择100例同期在本院接受体检并诊断为健康的汉族成年人为对照组。采用抑郁自评量表(SDS)评测抑郁情绪,采用哮喘控制测试量表(ACT)评估哮喘控制水平。采用ACT将126例哮喘患者分为未控制组(14例)、部分控制组(81例)、控制组(31例),分析抑郁情绪与哮喘控制水平关系。采用抑郁自评量表(SDS)将哮喘患者分为单纯哮喘组(76例)及哮喘合并抑郁组(50例),行肺功能检测,评估两组间肺功能差异。结果哮喘患者的抑郁发生率(39.68%)远高于对照健康人群(18.00%),差异有统计学意义(P0.05)。未控制组的抑郁指数高于部分控制组及控制组(P0.05),ACT评分与抑郁指数存在显著负相关(r=-0.438,P=0.000)。单纯哮喘组肺功能指标:FEV1、FVC、FEV1/FVC、PEF及ACT评分均较哮喘合并抑郁组明显降低,差异均有统计学意义(P0.05)。结论台州地区部分汉族哮喘患者抑郁发生率较高,抑郁与哮喘控制水平密切相关,抑郁可降低哮喘患者的肺功能。

Study on the correlation between the control level of bronchial asthma and depression in Han people in Taizhou area

Objective To investigate the correlation between the level of asthma control,pulmonary function and depression in the patients with bronchial asthma(asthma for short)in Han People in Taizhou area,and analyze the possible causes of depression in asthma patients.Methods 126 Han patients with asthma from the inpatient and outpatient of the department of respiratory medicine in our hospital were selected as the experimental group.At the same time,100 cases who received physical examination and were diagnosed as healthy Han adults in our hospital during the same period were selected as the control group.Depressive mood was evaluated by self-rating depression scale(SDS).Asthma control level was evaluated by asthma control test scale(ACT).126 asthmatic patients were divided into uncontrolled group(14 cases),partial controlled group(81 cases),and controlled group(31 cases)by evaluated by self-rating depression scale.The relationship between depression and asthma control was analyzed.The asthmatic patients were divided into simple asthma group(76 cases)and asthma complicated with depression group(50 cases)evaluated by asthma control test scale(ACT),and lung function test was carried out.The differences in lung function were evaluated between the two groups.Results The incidence rate of depression in asthmatic patients(39.68%)was significantly higher than that in healthy controls(18.00%),and the difference was statistically significant(P<0.05).The depression index in the uncontrolled group was higher than that in partially controlled group and controlled group(P<0.05).There was a significant negative correlation between ACT score and depression index(r=-0.438,P=0.000).Lung function indices in the simple asthma group:the scores of FEV1,FVC,FEV1/FVC,PEF and ACT were significantly lower than those in asthma complicated with depression group,and the difference was statistically significant(P<0.05).Conclusion The incidence rate of depression in the patients with asthma in Han People in Taizhou area is high.Depression and asthma control level are closely related.Depression can reduce lung function in asthmatic patients.