Abstract: | Dendritic and transcallosal potentials in the course of hyperthermia and after restoration of temperature homeostasis were investigated in experiments of waking rabbits exposed in a heat chamber to an air temperature of 45°C. The effect of the high temperature was accompanied by marked depression of the amplitude of the dendritic potential, although by a lesser degree than the transcallosal response. The results are evidence of the direct inhibitory effect of heat on neurons in the various layers of the cortex. Restoration of the function of the cortical neurons after a high degree of hyperthermia is observed 24 h after normothermia is reached.Central Research Laboratory, Rostov Medical Institute. (Presented by Academician V. N. Chernigovskii.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 8, pp. 931–933, August, 1976. |