毛细支气管炎发展为哮喘的影响因素分析

[目的]观察毛细支气管炎发展成为哮喘的发生率及影响因素。[方法]对198例毛细支气管炎进行回顾性分析,并与同期正常对照组208例进行比较。[结果]198例毛细支气管炎患儿中有59例发展成为哮喘,发生率为29.8%。而对照组哮喘的发生率为1.92%(4/208)。两组之间有显著差异(P<0.01)。毛细支气管炎患儿中有特应性体质、家族过敏史、父母吸烟及人工喂养等因素的患儿哮喘发生率较没有以上因素的患儿高(P<0.05或P<0.01)。[结论]毛细支气管炎易发展为哮喘,病毒感染和其他过敏原、遗传因素、个体特应性体质、环境因素等相互作用,共同参与了日后哮喘的发生。

Analysis on Influencing Factors of Bronchiolitis Developing into Asthma

[Objective] To observe the occurrence rate and influencing factors of bronchiolitis developing into asthma.[Method] Make retrospection analysis on 198 cases of bronchiolitis children,which are compared to 208 cases of normal control group.[Result] In 198 cases,59(29.8%) developed to asthma,and 1.92% for the control group(4/208);there's marked difference between two groups(P<0.01).The children with special constitution,family sensitive history,smoking parents and artificial feeding have higher occurrence rate than those without the factors(P<0.05 orP<0.01).[Conclusion] Bronchioitis developing into asthma concerns virus infection and other allergen,genetic factors,individual special constitution,and environmental factors.