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^18F-FDG PET/CT显像在食管癌分期中的应用
引用本文:张德全,;房娜,;崔新建.^18F-FDG PET/CT显像在食管癌分期中的应用[J].齐鲁肿瘤杂志,2009(22):1808-1810.
作者姓名:张德全  ;房娜  ;崔新建
作者单位:[1]莱西市肿瘤医院放射科,山东莱西266613; [2]青岛市中心医院放射科,山东青岛266600
摘    要:目的:探讨^18F-FDG PET/CT显像在食管癌分期中的应用价值。方法:对23例病理学确诊的食管癌患者,术前1周行全身PET/CT显像,根据病理结果评价PET/CT显像在食管癌分期中的应用价值。结果:19例患者进行了食管癌切除和淋巴结清除术,PET/CT显像发现50处病灶,与病理结果相比较,假阳性5处,假阴性3处,PET/CT诊断灵敏性为94%,特异性为76%;另4例患者因PET/CT发现多发转移而改变了治疗方案。结论:应用^18F-FDG PET/CT进行食管癌检查能显著提高分期的敏感性和准确性,具有较好的临床应用前景。

关 键 词:食管肿瘤  放射性核素显像  氟脱氧葡萄糖F18  敏感性与特异性  淋巴结转移

Applications of ^18F-FDG PET/CT in staging of esophageal carcinoma
Institution:ZHANG De-quan , FANG Na , CUI Xin-jian ( 1. Department of Radiology, Laixi Cancer Hospital, Laixi 266613, P. R. China 2. Department of Radiology, Qingdao Central Hospital, Qingdao 266600, P. R. China)
Abstract:OBJECTIVE: To evaluate the values of 18F-FDG PET/CT in staging of esophageal carcinoma.METHODS:^18F-FDG PET/CT was performed in 23 patients who were confirmed esophageal carcinoma by oesophagoscope before operation.^18F-FDG PET/CT results were compared with the post operation pathological results.RESULTS: Esophageal carcinoma and regional lymph nodes recection were performed in 19 patients.Of all the 50 lesions found by 18F-FDG PET/CT,there were 5 false-positive lesions and 3 false-negative lesions.^18F-FDG PET/CT showed a sensitivity of 94% and a specificity of 76% in preoperation staging of esophageal carcinoma.The other 4 patients,therapy were changed because generally remote metastastic lesions were found in ^18F-FDG PET/CT imaging.CONCLUSION:^18F-FDG PET/CT has higher sensitivity and specificity in the preoperation staging of esophageal carcinoma,and has better clinical perspective.
Keywords:esophageal neoplasms  radionuclide imaging  fluorodeoxyglucose ^18F  sensitivity and specificity  lymphatic metastasis
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