复方樟柳碱颞浅动脉旁注射治疗视神经炎37例

目的 观察复方樟柳碱治疗早期视神经炎的疗效.方法 将81例(93眼)视神经炙患者随机分为2组,治疗组37例41眼,对照组44例52眼;治疗组在与对照组同样的全身用药的同时,于患眼颞浅动脉旁注射复方樟柳碱注射液,每天1次,每次2 mL,1个月后观察2组患者治疗前后视力、视野、视觉诱发电位及眼底荧光血管造影的变化.结果 治疗组治愈37眼,有效率100.0%,对照组治愈33眼,有效率86.5%,二者比较差异有统计学意义(χ2=4.17>3.84,P<0.05).2组间视力变化、视野改变、视觉诱发电位及眼底荧光血管造影检查差异均有统计学意义(P均<0.05).结论 复方樟柳碱颞浅动脉旁注射治疗早期视神经炎,可有效改善视神经及其附近血液循环,增加血流量,改善血供,促进组织缺血、缺氧状况在较短时间内恢复,从而提高患者的视功能.

Hypodermic injection of compound anisodine around superficial temporal artery in 37 patients with optic neuritis

Objective To observe the therapeutic effects of the compound anisodine in treating the optic neuritis at its early stage. Methods Eighty-one optic neuritis patients(93 eyes) were randomly divided into two groups,experimental group(37 cases,41 eyes) and control group(44 cases,52 eyes). All patients were treated with systemic administration,and the patients of experimental group were also hypodermic injected with compound anisodine 2 mL around superficial temporal artery once a day. Variations in visual acuity, visual field, visual evoked potential as well as fluorescence fundus ungiography were examined and compared with that before treatment in both two groups. Besults Thirty-seven eyes in the experimental group were healed with a rate of 100.0% ,while 33 eyes in the control group were healed with a rate of 86.5%. There was statistically difference between the two groups(χ2 = 4.17 > 3.84 ,P < 0.05). There were statistically significant differences in the variations of visual acuity, visual field,visual evoked potential, and fluorescence fundus angiography between the two groups(All P< 0.05). Conclusions The hypodermic injection of compound anisodine in treating the optic neuritis at its early stage has proved effectively in improving the vigor of the optic nerves as well as blood circulation,increasing blood flow and supply, enhancing the restoration of tissue blood deficiency and oxygen deficiency within a short span of time,and finally heightening the visual power of patients.