| 低分子量肝素与阿司匹林联合治疗不稳定型心绞痛的临床观察 |
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| 引用本文： | 陈晓育. 低分子量肝素与阿司匹林联合治疗不稳定型心绞痛的临床观察[J]. 中国医学工程, 2005, 13(4): 395-397 |
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| 作者姓名： | 陈晓育 |
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| 作者单位： | 湖南省永州市第四人民医院,心血管内科,湖南,永州,425006 |
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| 摘 要： | 目的评价低分子量肝素(法安明)与阿司匹林联合治疗不稳定型心绞痛(UA)的临床疗效.方法将48例UA患者随机分为对照组(阿司匹林)及治疗组(法安明 阿司匹林),疗程为1周.结果1周后总有效率:治疗组87.5%,对照组66.7%(P＜0.05);观察2周治疗组无1例发生急性心肌梗死,对照组发生2例(8.3%);治疗组未发现明显不良反应.结论在常规治疗基础上加用法安明,能更有效地控制心绞痛发作,且安全方便.
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| 关 键 词： | 低分子量肝素 阿司匹林 不稳定型心绞痛 联合药物疗法 |
| 文章编号： | 1672-2019（2005）04-0395-03 |
| 收稿时间： | 2005-01-27 |
| 修稿时间： | 2005-01-27 |
Clinical observation of low-modecular-weight heparin combined with aspirin on patients with unstable angina |
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| CHEN Xiao-yu. Clinical observation of low-modecular-weight heparin combined with aspirin on patients with unstable angina[J]. China Medical Engineering, 2005, 13(4): 395-397 |
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| Authors: | CHEN Xiao-yu |
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| Abstract: | ObjectiveTo evaluate the clinical therapeutic efficacy of aspirin combined with Low- molecular- weight heparin (LMWH, fragmin) on the treatment of unstable angina (UA).Method48 patients with UA were randomized into a group receiving aspirin (the control group) and a group receiving aspirin plus LMWH( the treat- ment group) for one week.ResultThe effective rate was 87.5% in the treatment group and 66.7% in the control group after one week (P<0.05); No acute myocardial infarction occurred in the treating group, two cases had acute myocardial infarction in the control group after two weeks; no obvious adverse reaction was observed in the treatment group.ConclusionTreatment with aspirin plus LMWH is more efficient than aspirin alone during the acute stage of UA. Treatment with LMWH is safe and convenient. |
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| Keywords: | low-molecular-weight heparin aspirin unstable angina combined therapy |
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