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Multicentric reticulohistiocytosis associated with rheumatoid arthritis
Authors:Daichi Hoshina  Tadamichi Shimizu  Riichiro Abe  Junko Murata  Koichi Tanaka  Hiroshi Shimizu
Affiliation:(1) Department of Dermatology, Hokkaido University Graduate School of Medicine, Kita-ku, Sapporo, Japan;(2) Section of Orthopaedics, Japan Labour Health and Welfare Organization Iwamizawa Rhosai Hospital, Iwamizawa, Japan;(3) Department of Dermatology, Hokkaido University Graduate School of Medicine, Kita-ku, Sapporo 060-8638, Japan
Abstract:Due to the fact that both multicentric reticulohistiocytosis (MRH) and rheumatoid arthritis (RA) are destructive arthritic and skin disorders, it is often difficult to differentiate one from the other. Here, we report the case of a 67-year-old Japanese woman who had been diagnosed as suffering from RA 20 years ago, and who developed MRH. MRH may be misdiagnosed as RA, but evaluation of the time course of specific symptoms can greatly help in the correct diagnosis.
Keywords:Multicentric reticulohistiocytosis  Rheumatoid arthritis  Distal interphalangeal (DIP) joint  Methotrexate  Malignancy.
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