Multicentric reticulohistiocytosis associated with rheumatoid arthritis |
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Authors: | Daichi Hoshina Tadamichi Shimizu Riichiro Abe Junko Murata Koichi Tanaka Hiroshi Shimizu |
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Affiliation: | (1) Department of Dermatology, Hokkaido University Graduate School of Medicine, Kita-ku, Sapporo, Japan;(2) Section of Orthopaedics, Japan Labour Health and Welfare Organization Iwamizawa Rhosai Hospital, Iwamizawa, Japan;(3) Department of Dermatology, Hokkaido University Graduate School of Medicine, Kita-ku, Sapporo 060-8638, Japan |
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Abstract: | Due to the fact that both multicentric reticulohistiocytosis (MRH) and rheumatoid arthritis (RA) are destructive arthritic and skin disorders, it is often difficult to differentiate one from the other. Here, we report the case of a 67-year-old Japanese woman who had been diagnosed as suffering from RA 20 years ago, and who developed MRH. MRH may be misdiagnosed as RA, but evaluation of the time course of specific symptoms can greatly help in the correct diagnosis. |
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Keywords: | Multicentric reticulohistiocytosis Rheumatoid arthritis Distal interphalangeal (DIP) joint Methotrexate Malignancy. |
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