Identification of the C-terminal flanking peptide of preprocholecystokinin in rat brain by a novel radioimmunoassay |
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Authors: | Andrea Varro GJ Dockray |
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Abstract: | The C-terminal flanking peptide of preprocholecystokinin (preproCCK) has been identified in extracts of rat brain using a novel radioimmunoassay. There is a single form of immunoreactive material on gel filtration, ion exchange and reversed-phase HPLC. The C-terminal preproCCK immunoreactivity had a similar pattern of distribution to CCK8 in different regions of rat brain. This assay should help in studies of neuronal CCK biosynthesis. |
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Keywords: | preprocholecystokinin C-terminal flanking peptide radioimmunoassay rat brain |
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