低分子量肝素治疗进展型脑梗死及对血流变影响

目的:探讨低分子量肝素对进展型脑梗死的疗效及血流变影响.方法:将80例进展型脑梗死患者,随机分为治疗组40例,对照组40例.两组在治疗前后均行神经功能缺损评分和临床疗效评定,并观察其疗效及有关实验室指标,追踪随访1年.结果:治疗组的有效率明显高于对照组,不良反应轻微,PLT、APTT无明显变化,但血流变指标明显下降,1年内复发率明显小于对照组.结论:低分子肝素治疗进展型脑梗死疗效肯定,对于减少复发亦有一定作用,并可改善血流变.

Study of hemorrheology on low molecular weight heparin in treatment of acute ischemic stroke

OBJECTIVE To investigate the curative effect and hemorrheology effect of low molecular weight heparin (LMWH) in the treatment of acute ischemic stroke.METHODS 80 cases of acute ischemic stroke patients were studied by comparison randomly.There were 40 cases in therapy group and 40 cases in comparison group.The patients then were evaluated according to neurologic deficit and disability,the patients were observed for one year.RESULTS The validity rate of therapy group was higher than comparison group.Relapse rate within one year was less than the comparison group.CONCLUSION LMWH in treatment of acute ischemic stroke is safe and effective.