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Assessment of Dosing Impact on Intra-Individual Variability in Estimation of Parameters for Basic Indirect Response Models |
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| Authors: | Wojciech Krzyzanski Jacek Dmochowski Nobuko Matsushima William J. Jusko |
| Affiliation: | (1) Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, NY 14260, USA;(2) Department of Mathematics and Statistics, University of North Carolina, Charlotte, NC, USA;(3) Clinical Pharmacology and Biostatistics Department, Sankyo Co., Ltd., Tokyo, Japan |
| Abstract: | |
| Keywords: | pharmacodynamics indirect response models parameter estimates intra-individual variability bias precision |
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