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Multisystem Inflammatory Syndrome in Adult after First Dose of mRNA Vaccine |
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| Authors: | Yusuke Miyazato Kei Yamamoto Gen Yamada Shuji Kubota Masahiro Ishikane Masaya Sugiyama Mikako Ueno Akihiro Matsunaga Tohru Miyoshi-Akiyama Yukihito Ishizaka Norio Ohmagari |
| Affiliation: | National Center for Global Health and Medicine, Tokyo, Japan (Y. Miyazato, K. Yamamoto, G. Yamada, S. Kubota, M. Ishikane, M. Ueno, A. Matsunaga, T. Miyoshi-Akiyama, Y. Ishizaka, N. Ohmagari);National Center for Global Health and Medicine, Chiba, Japan (M. Sugiyama) |
| Abstract: | A 32-year-old man in Japan experienced respiratory failure after receiving the first dose of coronavirus disease (COVID-19) vaccine. He was treated with noninvasive ventilation and corticosteroids. Serologic test results suggested previous COVID-19; therefore, he received a diagnosis of multisystem inflammatory syndrome. COVID-19 vaccination could be a trigger for this condition. |
| Keywords: | COVID-19 coronavirus disease SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 vaccination respiratory failure myocardial injury MIS-A hyperinflammatory state cytokine profile anti-spike antibody anti-nucleocapsid antibody multisystem inflammatory syndrome Japan |