生姜、干姜炮制对厚朴挥发性成分影响比较

目的:探讨生姜、干姜及其炮制同一药物(厚朴)后挥发性成分的差异。方法:采用GC-MS对生姜、干姜、厚朴生品、生姜制厚朴和干姜制厚朴的挥发油类成分及其含量进行测定。结果:干姜中含有的挥发油总量高于生姜,干姜制厚朴挥发油总量也略高于生姜制厚朴;生姜中检测出9种化合物,干姜中检测出38种化合物,有4种化合物为两者共有;厚朴生品中发现16种成分,生姜制厚朴16种成分,干姜制厚朴17种成分,三者共同成分5种,生姜制厚朴和干姜制厚朴中两者共有成分14种,其中4种化合物生姜制姜厚朴相对质量分数高于干姜制姜厚朴,其余成分均为干姜制姜厚朴相对质量分数高于生姜制姜厚朴。结论:干姜和生姜制厚朴的挥发油在成分种类和含量上有一定区别,研究结果将为生姜、干姜的辅料作用差异奠定基础。

Comparative Analysis of Volatile Compositions in Zingeris Rhizoma Recens, Zingiberis Rhizoma and Processed Magnoliae Officinalis Cortex

Objective: To discuss the difference in volatile compositions between Zingeris Rhizoma Recens, Zingiberi Rhizoma and Zingeris Rhizoma Recens processed Magnoliae Officinalis Cortex or Zingiberi Rhizoma processed Magnoliae Officinalis Cortex. Method: GC-MS was applied to determine the volatile oil compositions and contents in Zingeris Rhizoma Recens, Zingiberi Rhizoma, raw Magnoliae Officinalis Cortex, Zingeris Rhizoma Recens processed Magnoliae Officinalis Cortex and Zingiberi Rhizoma processed Magnoliae Officinalis Cortex. Result: Total volatile oil content in Zingiberi Rhizoma was higher than that in Zingeris Rhizoma Recens. Total volatile oil content in Zingiberi Rhizoma processed Magnoliae Officinalis Cortex was also slightly higher than that in Zingeris Rhizoma Recens processed Magnoliae Officinalis Cortex. Nine components were found in Zingeris Rhizoma Recens and 38 components in Zingiberi Rhizoma, 4 in common. Sixteen components were found in raw Magnoliae Officinalis Cortex, 16 components in Zingeris Rhizoma Recens processed Magnoliae Officinalis Cortex, 17 components in Zingiberi Rhizoma processed Magnoliae Officinalis Cortex. Five components were in common among these three. Fourteen components were in common between Zingeris Rhizoma Recens processed Magnoliae Officinalis Cortex and Zingiberi Rhizoma processed Magnoliae Officinalis Cortex. In these 14 common components, the relative mass fraction of 4 components was higher in Zingeris Rhizoma Recens processed Magnoliae Officinalis Cortex than that in Zingiberi Rhizoma processed Magnoliae Officinalis Cortex, but the relative mass fraction in rest components was lower than that in Zingiberi Rhizoma processed Magnoliae Officinalis Cortex. Conclusion: There is difference in volatile oil compositions and contents between Zingeris Rhizoma Recens processed Magnoliae Officinalis Cortex and Zingiberi Rhizoma processed Magnoliae Officinalis Cortex. The results provide a better way to clarify the difference between Zingeris Rhizoma Recens and Zingiberi Rhizoma when they are considered as processing assistants.