养心汤治疗亚健康失眠69例临床分析

目的:观察养心汤加减治疗亚健康失眠的疗效及对生活质量的影响。方法:将140例亚健康失眠患者随机按1∶1原则分为对照组71例和观察组69例。对照组采用睡眠卫生宣教结合耳穴贴压的非药物疗法。观察组采用养心汤加减内服和沐足疗法。两组疗程均为4周。进行治疗前后匹兹堡睡眠质量指数(PSQI),WHO生活质量量表(WHOQOL-BREF)和临床医生总体印象(CGI)评分。结果:两组临床疗效经Ridit分析,观察组优于对照组(P0.05);两组治疗后PSQI各因子(睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物和日间功能)及总分较治疗前下降(P0.01);治疗后观察组PSQI各因子及总分低于对照组(P0.01);两组治疗后生理、心理、环境和社会关系领域评分均较治疗前升高(P0.01),治疗后观察组心理和社会关系2个维度评分高于对照组(P0.05);治疗后第2,3,4周两组CGI评分均比第1周下降(P0.05,P0.01),但组间比较差异无统计学意义。结论:加减养心汤内服和沐足干预亚健康失眠能改善睡眠质量,提高患者的生活,临床疗效确切。

Clinical Effect of Yangxin Decoction on Sub-health Insomnia in 69 Cases

Objective: To discuss the curative effect of Yangxin decoction in treating sub health insomnia and influence to quality of life. Method: One hundred and fourteen patients with sub health insomnia were randomly divided into control group (71 cases) and observation group (69 cases). Patients in control group received non-pharmaceutical therapy of sleep hygiene education combined with ear point tapping. Patients in observation group received addition and subtraction treatment of Yangxin decoction by oral taking and foot massage. Course of treatment was 4 weeks for both groups. Before and after treatment, scores of Pittsburgh sleep quality index (PSQI), WHO quality of life scale (WHOQOL-BREF) and the clinician Global Impression (CGI) were graded. Result: Ridit analysis showed that the clinical effect in observation group was superior to that in control group (P<0.05). After treatment, the scores of PSQI factors (sleep quality, time of falling asleep, sleep time, sleep efficiency, sleep disorders, hypnotic and day function) and the total scores were decreased compared with the data before treatment in both groups (P<0.01). Scores of PSQI factors and the total scores in observation group were lower than those in control group (P<0.01). After treatment, scores of physiology, mentality, environmental and social relations were higher than the data before treatment (P<0.01). And scores of mentality and social relations in observation group were higher than those in control group (P<0.05). CGI scores were decreased in the second, third, and fourth weeks compared with the data at first week in both groups (P<0.05, P<0.01). There was no statistically significant difference between two groups. Conclusion: Addition and subtraction treatment of oral Yangxin decoction and foot massage intervention can improve the quality of sleep and enhance the life of patients in sub-health insomnia. The clinical effect is clear.