小儿腹泻散与双歧杆菌四联活菌片联合治疗婴幼儿轮状病毒腹泻的疗效观察

目的观察小儿腹泻散与双歧杆菌四联活菌片联合治疗婴幼儿轮状病毒腹泻的疗效。方法将婴幼儿轮状病毒腹泻的患儿180例随机分为治疗组和对照组，各90例。治疗组在常规治疗基础上加用小儿腹泻散与双歧杆菌四联活菌片治疗；对照组仅给予抗病毒、补液、纠正酸中毒、维持水电解质平衡及抗炎等常规治疗。观察2组疗效。结果治疗组总有效率达96．7％高于对照组的85．6％，差异有统计学意义（P〈0．05）。治疗组腹泻总疗程短于对照组，差异有统计学意义（P〈0．05）。2组在治疗过程中均无不良反应，治疗前后肝功能、血尿常规检查无异常改变。结论小儿腹泻散与双歧杆菌四联活菌片联合治疗婴幼儿轮状病毒腹泻，安全有效，有利于恢复肠道微生态平衡，止泻效果显著，值得临床进一步推广应用。

The clinical research of Xiaoerfuxie powder and tetralogy of viable bifidobacterium tablets for infant joint rotavirus driarrhea

Objective To observe Xiaoerfuxie powder and tetralogy of viable bifidobacterium tablets combination ther- apy for infant rotavirus curative effect. Methods 180 cases of children with rotavirus diarrhea were randomly divided into treatment group and control group, each of 90 cases. Treatment group was treated with Xiaoerfuxie powder and tetralogy of viable bifidobacterium tablets;Control group were given anti-viral, fluid, and corrected acidosis, maintained fluid and electrolyte balance and anti-inflammatory. Observed effects of two groups. Results The total effective rate of treatment group was 96.7% higher than 85.6% in contral group, the difference was statistically significant（ P 〈 0.05 ）. Diarrhea, the total course of treat- ment shorter than that of control group ,the difference was statistical｜y significant（ P 〈0.05 ）. Two group had no adverse reac- tions during treatment;Liver function before and after treatment, no abnormal changes in blood and urine routine examination. Conclusion Xiaoerfuxie powder and tetralogy of viable bifidobacterium tablets combination therapy for infant rotavirus diar- rhea has safe and effective, to restore intestinal microecological balance, diarrhoea. It is worth further popularized.