番禺地区婴幼儿药品不良反应分析

目的分析番禺地区婴幼儿药品不良反应（ADR）发生的特点与一般规律,促进临床合理用药。方法对番禺地区各医院收集和上报的187例婴幼儿ADR报告,分别从给药途径、药品种类、涉及器官或系统以及临床表现等方面进行统计、分析。结果 187例ADR中,176例（94.1%）是以静脉给药的方式引发的;最易引起ADR的药品为抗感染药,占总例数的66.3%（124例）;最常见的临床表现为皮肤及其附件损害,占总例数的76.5%（143例）。结论应减少不合理用药现象,加强ADR监测报告工作,减少或避免ADR的发生。

Analysis of ADR in Nursling in Panyu distric

Objective To analyze the featurel and general patterns of adverse drug reaction（ADR）in nursling occurred in Panyu district,in order to promote rational clinical drug use.Methods 187 case of ADR reports collected in Panyu district were analyzed statistically in respect of route of administration,category of the drugs,organs and systems involved and clinical manifestation etc.Results In 187 cases of ADR,176 cases（94.1%）were induce through intravenous way;Most likely caused by ADR for the anti-infective drugs,with a proportion of 66.3%（124 cases）;The most common clinical manifestations of skin and its appendages,with a proportion of 76.5%（143 cases）.Conclusion The phenomenon of irrational drug use should be reduced and the ADR monitor work should be strengthen to avoid or reduce the incidence of ADR.