| 慢性肾衰血透患者骨代谢的评估 |
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| 引用本文： | 章俊 曾熙兰. 慢性肾衰血透患者骨代谢的评估[J]. 标记免疫分析与临床, 1997, 4(3): 139-142 |
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| 作者姓名： | 章俊 曾熙兰 |
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| 作者单位： | [1]第一军医大学珠江医院 [2]中山医科大学放免中心 |
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| 摘 要： | 用ＩＲＭＡ、ＲＲＡ和ＲＩＡ等对２４例维持血透患者（ＭＨＤ）测定其血甲状旁腺激素、ＰＴＨ（１￣８４）、２５（ＯＨ）Ｄ３、１，２５（ＯＨ）２Ｄ３、ＢＧＰ、血钙和磷的变化，以探讨它们之间的关系和评估患者骨代谢的状况。ＭＨＤ患者ＰＴＨ和ＢＧＰ升高，透析后则降低；２５（ＯＨ）Ｄ３和１，２５（ＯＨ）２Ｄ３降低，透析对其无明显影响；ＰＴＨ与２５（ＯＨ）Ｄ３、１，２５（ＯＨ）２Ｄ３呈负相关，Ｐ分别小于０．０５和０
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| 关 键 词： | 肾功能衰竭 慢性 血液透析 骨代谢 |
Evaluation of Bone Metabolism in Patients with Chronic Renal Failure Maintained by Hemodialysis |
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| Zhang Jun, Zeng Xilan, Zeng Li. Evaluation of Bone Metabolism in Patients with Chronic Renal Failure Maintained by Hemodialysis[J]. Labeled Immunoassays and Clinical Medicine, 1997, 4(3): 139-142 |
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| Authors: | Zhang Jun Zeng Xilan Zeng Li |
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| Abstract: | The changes of PTH, 25(OH)D3, 1, 25(OH)2D3, BGP, Ca and P levels in the blood of 24 hemodialysis patients and their relationship were investigated by IRMA, RRA and RIA. PTH and BGP were increased in HD patients and decreased after hemodialysis. 25(OH)D3and 1, 25 (OH)2D3 were decreased in patients, but their levels were not changed further after hemodialysis. PTH had both a negative correlation with 25(OH)D3 (r=-0. 391, P < 0. 05) or 1, 25(OH)2D3(r=-0. 493, P< 0. 01), and a positive correlation with BGP (r=0. 517, P<0.01) in HD patients. PTH hypersecretion is a main factor inducing bone metabolism disturbance and bone turnover rate is increased in these patients. |
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| Keywords: | Renal failure chronic Hemodialysis Parathyroid hormone Osteocalcin Vitamin D |
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