| Abstract: | ? Proton pump inhibitors are currently used widely for the treatment of laryngopharyngeal reflux. ? This systematic review assessed the efficacy of proton pump inhibitors in the treatment of symptoms of laryngopharyngeal reflux. ? Outcome measures used to assess efficacy of proton pump inhibitors included endoscopic laryngeal signs and pH recordings. ? Only two small randomized‐controlled trials included patients with objective evidence of reflux in the 24‐h ambulatory oesophageal pH monitoring. ? Pooled analysis of these two randomized‐controlled trials failed to show any effect in favour of treatment with proton pump inhibitors. ? Further randomized‐controlled trials are required to ascertain the role of proton pump inhibitors in the treatment of laryngopharyngeal reflux. |
