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巨细胞病毒对乙肝患者危害的研究
引用本文:苏洁寒,谢志春,梁浩.巨细胞病毒对乙肝患者危害的研究[J].应用预防医学,2002,8(3):135-137.
作者姓名:苏洁寒  谢志春  梁浩
作者单位:广西医科大学公共卫生学院,南宁,530021
摘    要:目的:了解不同类型肝炎患者及健康人感染巨细胞病毒(CMV)状态及临床特征。方法:用聚合酶链反应(PCR)检测321例不同人群血清中CMV-DNA。结果:乙肝患者CMV-DNA总检出率为34.2%,健康人为4.4%。乙肝患者分型检测CMV-DNA阳性率为:急肝17.7%、慢性肝19.4%、慢中肝45.4%、慢重肝51.6%、肝硬化37.2%。结论:CMV-DNA在不同人群中均能检出。乙肝患者分型检测CMV-DNA的阳性率提示活动性CMV感染可能使乙肝患者病情加重。

关 键 词:巨细胞病毒  聚合酶链反应  乙型肝炎
文章编号:1007-158X(2002)03-0135-03
修稿时间:2001年12月20

Cytomegalovirus (CMV) infection in patients with hepatitis B
SU Jiehan,XIE Zhichun,LIANG Hao.School of Publil Health,Guangxi Medical University,Nanning.Cytomegalovirus (CMV) infection in patients with hepatitis B[J].Journal of Applied Preventive Medicine,2002,8(3):135-137.
Authors:SU Jiehan  XIE Zhichun  LIANG HaoSchool of Publil Health  Guangxi Medical University  Nanning
Institution:SU Jiehan,XIE Zhichun,LIANG Hao.School of Publil Health,Guangxi Medical University,Nanning 530021
Abstract:Objective To investigate the prevalences of CMV infection in patients with hepatitis B and health control.Methods CMV infection was determined in 321 people by polymerase chain reaction(PCR).Results CMV DNA was detected in 34.2% of patients with hepatitis B and in 4.4% of health control.The positive rates of CMV DNA were 17.7% in acute hepatitis,19.4% in chronic light hepatitis,51.6% in chronic severe hepatitis and 37.2% in liver cirrhosis.Conclusion CMV DNA can be detected in all kinds of hepatitis B and health control.Our results suggest that CMV infection may aggravate the impairment on health of patients with hepatitis B.
Keywords:CMV-DNA    PCR    Patient with hepatitis B
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