Bilateral non-arteritic anterior ischemic optic neuropathy following second-trimester spontaneous abortion-related haemorrhage |
| |
| Authors: | Zafer Onaran Funda Uysal Tan Pelin Yılmazbaş Yüksel Onaran |
| |
| Affiliation: | 1. Department of Ophthalmology, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey;2. Department of Neurology, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey;3. Department of Gynaecology and Obstetrics, Faculty of Medicine, Fatih University, Ankara, Turkey;1. Cancer Research UK, Cambridge Cancer Research Institute, Robinson Way, Cambridge CB2 0RE, UK;2. The Department of Applied Mathematics and Theoretical Physics, Cambridge University, Cambridge, UK;3. Department of Neurosurgery and Brain Tumor and Neuro-Oncology Center, The Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA;4. Case Western Reserve University School of Medicine, Cleveland, Ohio, USA;1. Department of Pediatrics, Faculty of Medicine, University of Gaziantep, Gaziantep, Turkey;2. Division of Neonatology, Department of Pediatrics, Faculty of Medicine, University of Gaziantep, Gaziantep, Turkey;3. Department of Medical Biology, Faculty of Medicine, University of Gaziantep, Gaziantep, Turkey;4. Department of Pediatrics, Faculty of Medicine, Sanko University, Gaziantep, Turkey;5. Department of Medical Pharmacology, Faculty of Medicine, University of Gaziantep, Gaziantep, Turkey;1. Department of Ophthalmology, University of California, Davis, Sacramento, California;2. Department of Biomedical Engineering, Duke University, Durham, North Carolina;3. Department of Ophthalmology, Duke University, Durham, North Carolina |
| |
| Abstract: | Bilateral anterior ischemic optic neuropathy is a rare complication of massive haemorrhage and related hypotension and anaemia in young individuals. We report a 34-year-old woman with bilateral non-arteritic ischemic optic neuropathy (NAION) after a massive spontaneous abortion-related haemorrhage who presented with sudden painless visual loss in her left eye. Visual acuity was 20/20 in the right eye with only hand motion discernible in the left eye. There was a left relative afferent papillary defect (RAPD). Fundus examination revealed bilateral swollen, hyperaemic optic discs and nerve fiber layer haemorrhages. Brain MRI and magnetic resonance venography were normal. The diagnosis of bilateral NAION was made and intravenous pulse corticosteroid therapy (1000 mg/day) was administered for three days. On the sixth day, optic disc oedema regressed bilaterally and on the third week, the visual acuity improved to 20/80 in the left eye. The visual field showed only a small spared area in the nasal region, and persistent RAPD was present. After two months, fundus examination showed a small and crowded optic disc on the right and a pale optic disc on the left. Severe acute haemorrhage is an important risk factor for NAION in healthy young individuals. In addition to correction of hypotension and anaemia, intravenous high dose corticosteroid might be beneficial for treatment. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
