冠状动脉微血管疾病评估技术新进展

冠状动脉微血管疾病(CMVD)与心血管疾病的不良预后密切相关,是近年来的研究热点。但由于冠脉造影术无法直接观察到冠状动脉微循环系统,CMVD的诊断通常是基于对微循环的功能评估,目前临床使用侵入性检测方式(例如:冠状动脉内多普勒导丝、微循环阻力指数等)跟非侵入性检测方式(正电子发射断层扫描、心脏核磁共振等)对微循环功能进行间接评估。各种检测方式在评估微循环功能方面具有不同的优势和局限。本文主要对CMVD近年来评估方式的研究进展进行综述,以期提高临床医务工作者对CMVD评估技术的认识。

New progress in assessment techniques for coronary microvascular disease

Coronary microvascular disease (CMVD) is closely associated with poor prognosis of the cardiovascular diseases and has been a research focus in recent years. However, coronary angiography cannot directly visualize the coronary microcirculatory system, and invasive methods (intracoronary Doppler guidewire, microcirculatory resistance index, etc.) and non-invasive methods (positron emission tomography, cardiac magnetic resonance, etc.) are currently used to indirectly assess microcirculatory functions with their own advantages and limitations. This article mainly reviews the research progress of CMVD assessment modalities in recent years to improve the understanding of CMVD assessment techniques among clinical practitioners.