| 85例缺血性脑血管病患者血浆CGRP、NPY的改变 |
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| 引用本文： | 陈军,单益民,张忠平.85例缺血性脑血管病患者血浆CGRP、NPY的改变[J].实用临床医学(江西),2003,4(4):15-16. |
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| 作者姓名： | 陈军 单益民 张忠平 |
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| 作者单位： | 南昌市第一人民医院神经内科 江西南昌330008
(陈军，单益民)，南昌市第一人民医院神经内科 江西南昌330008(张忠平) |
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| 摘 要： | 目的 :探讨缺血性脑血管病两种神经肽与疾病的关系。方法 :应用放射免疫法检测急性缺血性脑血管病血浆中CGRP、NPY的含量 ,结果 :急性脑梗塞患者CGRP显著低于健康对照组 (P <0 .0 1) ;NPY则显著高于健康对照组 (P <0 .0 1)。结论 :CGRP、NPY参与缺血性脑血管病的发病过程。
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| 关 键 词： | 脑梗塞 降钙素基因相关肽 神经肽γ |
| 文章编号： | 1009-8194(2003)04-0015-02 |
| 修稿时间： | 2003年3月21日 |
Change of the Levels of CGRP and NPY in Blood Plasma of 85 Patients with Ischemic Stroke |
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| Chen Jun,Shan Yi min,Zhang Zhong ping.Change of the Levels of CGRP and NPY in Blood Plasma of 85 Patients with Ischemic Stroke[J].Practical Clinical Medicine,2003,4(4):15-16. |
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| Authors: | Chen Jun Shan Yi min Zhang Zhong ping |
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| Abstract: | objective: To investigate the relationship between two plasmic neuropeptides and ischemic stroke.Methods:Radioactive ivityimmunoassay was used to determine the content of plasmic Calcitonin gene related Peptide and Neuropeptide Y in patients with acute ischemic stroke.Results:The level of CGRP in the group of cerebral infarction was marked lower than that in the group of normal adult( P <0.01);The level of NPY in the group of cercbral infarction was marked higher than that in the group of normal adult( P <0.01).Conclusion:Calcitionin gene related peptide and Neuropeptide Y play a role in the pathogenesis of ischemic stroke. |
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| Keywords: | cerebral infarction calcitonin gene related peptide neurope ptide Y |
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