阻塞性睡眠呼吸暂停低通气综合症对睡眠结构及睡眠期血氧饱和度的影响

目的:探索不同程度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者之间的呼吸障碍的差异以及连续血氧饱和度(SaO2)检测是否对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)有诊断价值。方法:对259例鼾症患者进行多导睡眠图(PSG)的检测,分为单纯鼾症、轻、中、重度OSAHS共4组,收集资料并分析。结果:OSAHS组的体重、BM I均显著高于单纯鼾症组(P均<0.05)与单纯鼾症患者比较,OSAHS患者的浅睡眠%增加、深睡眠%减少,差异显著(P均<0.05)。在所有的鼾症患者中,BM I与睡眠呼吸暂停低通气指数(AH I)呈显著正相关(R=0.45;P=0.000);各OSAHS组SaO2的基础值和最低值均小于单纯鼾症组(P均<0.05);所有患者的SaO2的基础值与AH I呈显著负相关(R=-0.66,P<0.05);若以SaO2基础值<94%和SaO2<85%作为诊断OSAHS的标准,敏感性分别是67.11%和7.67%;特异性分别是100%和97.06%。结论:在单纯鼾症和OSAHS之间存在体重、BM I的显著差异,BM I与AH I显著正相关;OSAHS患者的浅睡眠比单纯鼾症患者明显增加。OSAHS患者存在睡眠时SaO2下降,并与疾病的严重程度有关;连续检测SaO2是在鼾症患者中鉴别出OSAHS的一个有效的简易方法。

Successive oximetric data and sleeping architecture on simple snore and OSAHS

Objective: To explore successive oximetric data and sleeping architecture on simple snore and OSAHS.Methods: The successive oximetric data and general parameters and polysomnography parameters of 34 simple snore patients and 225 OSAHS patients were analysised.Results: Compared with simple snore,the weight and BMI of OSAHS were increased obviously(P<0.05).Compared with simple snore,there were much more somnolence,fewer deep sleep(P<0.05).There were significant positive corralative between AHI and BMI in the all snore patients.Compared with simple snore patients,mean value and minimum value of SaO2(SaO2mean and SaO2mini) is significant degression in all OSAHS patients;There was a significant negative correlation between AHI and SaO2mean in all subjects;When predictive value of OSAHS is SaO2mean and SaO2mini smaller then 94% and 85% respectively,sensitivity is 67.11% and 7.67% respectively,specificity 100% and 97.06%.Conclusion: Compared with simple snore,weight and BMI in the OSAHS patients were obviously increased.There were significant positive correlation between BMI and AHI in the all snore patients.There were much more somnolence and fewer deep sleep in the OSAHS then in the simple snore.SaO2 during sleep is deterioration in OSAHS patients,and was a significant negative correlation with AHI;successive oximetric criteria have better dignosis value towards OSAHS.