| 18F-脱氧葡萄糖正电子发射计算机断层显像在库欣病诊断和术前定位中的价值 |
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| 引用本文： | Xin C,Rui-xue C,Hui P,Tao Y,Hui-Juan Z,Fang L. 18F-脱氧葡萄糖正电子发射计算机断层显像在库欣病诊断和术前定位中的价值[J]. 中国医学科学院学报, 2011, 33(2): 107-110. DOI: 10.3881/j.issn.1000-503X.2011.02.001 |
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| 作者姓名： | Xin C Rui-xue C Hui P Tao Y Hui-Juan Z Fang L |
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| 作者单位： | 1. 中国医学科学院,北京协和医学院,北京协和医院,核医学科,北京,100730
2. 中国医学科学院,北京协和医学院,北京协和医院,内分泌科,北京,100730 |
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| 摘 要： | 目的 评价18F-脱氧葡萄糖(<'18>FDG)正电子发射计算机断层显像 (PET)/CT在库欣病定性和定位诊断中的价值.方法 12 例经口鼻蝶窦垂体腺瘤切除后病理证实为库欣病患者,术前行<'18> FDG PET/CT躯干和脑显像,同期行鞍区核磁共振成像 (MRI)和奥曲肽全身显像,6例行岩下窦静脉取血 (IPSS).结果 12 例PET/CT 躯干显像均未见异常,脑显像对垂体病变诊断的阳性率为91.6%(11/12),MRI对垂体病变诊断的阳性率为66.7%(8/12),6例IPSS 中5例定位为垂体,定侧准确率为50%(3/6).结论 <'18>FDG PET/CT躯干显像可协助除外异位促肾上腺皮质激素综合征,而脑显像对库欣病定位的准确率明显高于MRI,尤其对MRI检查阴性和IPSS无法定位患者的术前诊断有重要意义.
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| 关 键 词： | 库欣病 正电子发射计算机断层显像 垂体腺瘤 《'18》F-脱氧葡萄糖 |
Value of [18F] fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in diagnosis and localization of Cushing's disease |
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| Xin Cheng,Rui-xue Cui,Hui Pan,Tao Yuan,Hui-Juan Zhu,Fang Li. Value of [18F] fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in diagnosis and localization of Cushing's disease[J]. Acta Academiae Medicinae Sinicae, 2011, 33(2): 107-110. DOI: 10.3881/j.issn.1000-503X.2011.02.001 |
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| Authors: | Xin Cheng Rui-xue Cui Hui Pan Tao Yuan Hui-Juan Zhu Fang Li |
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| Affiliation: | CHENG Xin1,CUI Rui-xue1,PAN Hui2,YUAN Tao2,ZHU Hui-juan2,LI Fang11Department of Nuclear Medicine,2Department of Endocrinology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China |
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| Abstract: | Objective To explore the value of [18F] fluoro-2-deoxy-D-glucose(18FDG) positron emission tomography and computer tomography(PET/CT) in the qualitative diagnosis and localization of Cushing's disease.Methods Totally 12 patients underwent transsphenoidal adenomectomy and were histopathologically proven to be with Cushing's disease.18FDG PET/CT whole-body and brain scannings were performed preoperatively;meanwhile,magnetic resonance imaging(MRI) and 99mTc-octreotide examination were done in all 12 cases,and i... |
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| Keywords: | Cushing's disease positron emission tomography pituitary adenomas [18F]fluoro-2-deoxy-D-glucose |
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