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正常心肌代谢显像18氟-脱氧葡萄糖摄取状况的初步探讨
引用本文:许光,宋丽萍,杨敏福,杨旭. 正常心肌代谢显像18氟-脱氧葡萄糖摄取状况的初步探讨[J]. 中国医学影像学杂志, 2011, 19(6): 408-411. DOI: 10.3969/j.issn.1005-5185.2011.06.003
作者姓名:许光  宋丽萍  杨敏福  杨旭
作者单位:1. 辽宁医学院附属第一医院核医学科辽宁锦州,121000
2. 北京阜外心血管病医院核医学科,北京,100037
摘    要:目的探讨正确的18氟-脱氧葡萄糖(18F-Fluorodeoxyglucose,18F-FDG)心肌缺血显像方法。资料与方法两组各9名受试者分别于禁食状态下接受一日法、两日法静息、运动18F-FDG心肌代谢显像。定量分析两种显像方法在静息和运动状态下心肌18F-FDG摄取的差异。结果两日法运动状态下的正常心肌18F-FDG摄取不符合18F-FDG示踪动力学。而一日法运动状态下正常心肌18F-FDG的最大标准化摄取值(SUVheart)与肝实质的SUVliver比值及心肌与心血池的SUV比值(SUVheart/SUVliver;SUVheart/SUVblood pool)明显高于静息状态(2.07±1.44,1.31±0.81,P<0.05;2.61±0.80,1.75±0.52,P<0.05)。且三支冠脉血管区域之间18F-FDG摄取差异无统计学意义。一日法静息、运动18F-FDG心肌代谢显像,运动后各节段心肌18F-FDG摄取成比例明显增加,符合负荷心肌18F-FDG示踪动力学。结论本研究证实,一日法静息和运动18F-FDG心肌代谢显像可成为运动诱发冠心病心肌缺血的无创诊断方法。

关 键 词:心肌缺血  氟脱氧葡萄糖F18  正电子发射断层显像术

Preliminary Investigation of the 18F-Fluorodeoxyglucose Induced in Normal Myocardial Metabolic Imaging
XU Guang,SONG Liping,YANG Minfu,YANG Xu. Preliminary Investigation of the 18F-Fluorodeoxyglucose Induced in Normal Myocardial Metabolic Imaging[J]. Chinese Journal of Medical Imaging, 2011, 19(6): 408-411. DOI: 10.3969/j.issn.1005-5185.2011.06.003
Authors:XU Guang  SONG Liping  YANG Minfu  YANG Xu
Affiliation:XU Guang SONG Liping YANG Minfu YANGXu Department of Nuclear Medicine,the First Affiliated Hospital of Liaoning Medical College,Jinzhou,Liaoning,121000
Abstract:Purpose To evaluate the right method of myocardial imaging with 18F-Fluorodeoxyglucose (18F-FDG) in myocardial ischemia. Materials and Methods Eighteen subjects were divided into 2 groups. Under fasting state, either group accepted the one-day or the two-day rest and exercise 18F-FDG myocardial metabolic imaging respectively. The difference of normal myocardial 18F-FDG uptake was analyzed by quantitative analysis between rest and stress conditions in two methods. Results The normal myocardial 18F-FDG uptake...
Keywords:] Myocardial ischemia  Fluorodeoxyglucose F18  Positron-emission tomography  
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