| 乳腺癌超声表现与分子生物学指标的相关性研究 |
| |
| 引用本文： | 田丽元,陈东风,曹长军,王少春.乳腺癌超声表现与分子生物学指标的相关性研究[J].中国医学影像学杂志,2011,19(6):468-471,475. |
| |
| 作者姓名： | 田丽元 陈东风 曹长军 王少春 |
| |
| 作者单位： | 1. 天津医科大学,天津,300070
2. 济宁医学院附属医院超声科,山东济宁,272029 |
| |
| 摘 要： | 目的初步探讨乳腺癌超声表现与分子生物学指标雌激素受体(ER)、孕激素受体(PR)、人表皮生长因子受体-2(CerbB-2)的相关性。资料与方法回顾性观察137例病理确诊为乳腺癌的超声图像与石蜡切片,分析超声征象与ER、PR、CerbB-2的关系。结果肿块纵横比>1与ER、PR阳性表达相关(χ2=11.551,P<0.05;χ2=5.973,P<0.05);边缘毛刺征与ER、PR阳性表达相关(χ2=7.883,P<0.05;χ2=5.600,P<0.05);高回声晕征与ER、PR阳性表达相关(χ2=8.108,P<0.05;χ2=4.957,P<0.05);肿块内部坏死与PR阴性表达相关(χ2=4.819,P<0.05);微钙化与CerbB-2阳性表达相关(χ2=4.661,P<0.05)。结论乳腺癌超声表现与分子生物学指标有一定的相关性,可根据乳腺癌超声表现预测其生物学行为,为临床治疗方案的选择与预后评估提供依据。
|
| 关 键 词： | 乳腺肿瘤 超声检查 生物学标记 |
Correlation between Ultrasonographic Features and Molecular Markers of Breast Cancer |
| |
| TIAN Liyuan,CHEN Dongfeng,CAO Changjun,WANG Shaochun.Correlation between Ultrasonographic Features and Molecular Markers of Breast Cancer[J].Chinese Journal of Medical Imaging,2011,19(6):468-471,475. |
| |
| Authors: | TIAN Liyuan CHEN Dongfeng CAO Changjun WANG Shaochun |
| |
| Institution: | TIAN Liyuan CHEN Dongfeng CAO Changjun WANG Shaochun Department of Ultrasound,Affiliated Hospital of Jining Medical University,Jining,Shandong,272029 |
| |
| Abstract: | Purpose To study the correlation between the ultrasonographic features and molecular markers, including estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (CerbB-2) in patients with breast cancer. Materials and Methods The ultrasonographic features and paraffin section of 137 cases of breast cancer confirmed by histopathology were observed retrospectively. The correlation between ultrasonographic features and molecular markers, including ER, PR and CerbB-2 were ... |
| |
| Keywords: | Breast neoplasms Ultrasonography Biological markers |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
