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经直肠实时组织弹性成像在前列腺癌诊断中的作用
引用本文:张艳,唐杰,李岩密,费翔,程流泉,何恩辉,李秋洋. 经直肠实时组织弹性成像在前列腺癌诊断中的作用[J]. 中国医学科学院学报, 2011, 33(2). DOI: 10.3881/j.issn.1000-503X.2011.02.015
作者姓名:张艳  唐杰  李岩密  费翔  程流泉  何恩辉  李秋洋
作者单位:解放军总医院超声科,北京,100853
摘    要:目的 探讨经直肠实时组织弹性成像(TRTE)在诊断前列癌(PCa)中的作用.方法 对84例疑为PCa并准备行穿刺活检的患者进行TRTE、直肠指诊(DRE)、经直肠超声(THUS)及磁共振(MRI)检查,将弹性成像与其他检查及病理结果相比较.结果 84例患者中良性36例、恶性48例.TRTE诊断的灵敏度(91.7%)、特异度(72.2%)、准确率(83.3%)、阳性预测值(81.5%)及阴性预测值(86.7%)与TRUS(灵敏度85.4%、特异度63.9%、准确率76.2%、阳性预测值75.9%、阴性预测值76.7%)诊断的差异无统计学意义(P>0.05),其诊断的特异度72.2%高于MRI的44.4%(P=0.03).TRTE诊断与病理的符合率和血清总前列腺特异抗原水平无关(P>0.05),其诊断的灵敏度随前列腺体积的增大而降低.对DRE检查呈软一中等质地的结节,TRTE诊断的特异度高于MRI(P=0.04).对于PCa,TRTE诊断的灵敏度随肿瘤Gleason评分的增加而提高(P<0.05).结论 TRTE可作为诊断PCa的一种重要的补充手段,为临床提供帮助.

关 键 词:前列腺癌  超声  弹性成像

Role of Transreetal Real-time Tissue Elastography in the Diagnosis of Prostate Cancer
ZHANG Yan,TANG Jie,LI Yan-mi,FEI Xiang,CHENG Liu-quan,HE En-hui,LI Qiu-yang. Role of Transreetal Real-time Tissue Elastography in the Diagnosis of Prostate Cancer[J]. Acta Academiae Medicinae Sinicae, 2011, 33(2). DOI: 10.3881/j.issn.1000-503X.2011.02.015
Authors:ZHANG Yan  TANG Jie  LI Yan-mi  FEI Xiang  CHENG Liu-quan  HE En-hui  LI Qiu-yang
Affiliation:ZHANG Yan,TANG Jie,LI Yan-mi,FEI Xiang,CHENG Liu-quan,HE En-hui,LI Qiu-yang Department of Ultrasound,PLA General Hospital,Beijing 100853,China
Abstract:Objective To investigate the role of transrectal real-time tissue elastography(TRTE) in the diagnosis of prostate cancer(PCa).Methods Eighty-four patients with suspected PCa and scheduled for prostate biopsies underwent TRTE,digital rectal examination(DRE),transrectal ultrasonography(TRUS),and magnetic resonance imaging(MRI).The findings of TRTE were compared with those of other examinations and pathological findings.Results Of these 84 patients,36 had benign lesions and 48 had PCa.The diagnostic sensitivit...
Keywords:prostate cancer  ultrasound  elastography  
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