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| 胰泰复方对慢性胰腺炎胰腺纤维化大鼠血清Ⅲ型前胶原氨基端肽含量的影响 | |
| 引用本文： | 刘华生,林旭红,周景华.胰泰复方对慢性胰腺炎胰腺纤维化大鼠血清Ⅲ型前胶原氨基端肽含量的影响[J].中国中医急症,2007,16(8):971-972. |
| 作者姓名： | 刘华生 林旭红 周景华 |
| 作者单位： | 1. 黑龙江中医药大学基础医学院,哈尔滨,150040 2. 黑龙江中医药大学,哈尔滨,150040 3. 黑龙江中医药大学附属医院,哈尔滨,150040 |
| 摘 要： | 目的观察中药胰泰复方对慢性胰腺炎胰腺纤维化大鼠血清Ⅲ型前胶原氨基端肽（PⅢNP）含量的影响。方法以精氨酸左下腹腔注射制备大鼠慢性胰腺炎模型，予相应药物灌胃治疗，2个月后取血清用双抗体夹心ABC—ELISA法测定PⅢNP的含量。结果模型组PⅢNP含量明显高于空白组、中药对照组及中药治疗组，中药治疗组PⅢNP含量低于中药对照组。结论胰泰复方能降低血清中PⅢNP的含量，对慢性胰腺炎胰腺纤维化具有恢复作用。 |
| 关 键 词： | 慢性胰腺炎 胰腺纤维化 胰泰复方 Ⅲ型前胶原氨基端肽 |
| 文章编号： | 1004-745X（2007）08-0971-02 |
| 收稿时间： | 2007-01-04 |
| 修稿时间： | 2007年1月4日 |
Effect of YITAI Compounded Medication on Contents of Procollagen Ⅲ N - terminal Peptide of the Rats with Chronic Pancreatitis Fibrosis |
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| LIU Hua-sheng,LIN Xu-hong,ZHOU Jing-hua.Effect of YITAI Compounded Medication on Contents of Procollagen Ⅲ N - terminal Peptide of the Rats with Chronic Pancreatitis Fibrosis[J].Journal of Emergency in Traditional Chinese Medicine,2007,16(8):971-972. | |
| Authors: | LIU Hua-sheng LIN Xu-hong ZHOU Jing-hua |
| Institution: | 1.Basic medical College of Heilongjiang University of Traditional Chinese Medicine Haerbin 150040; 2.Graduate student of 2004 of Heilongjiang University of Traditional Chinese Medicine Haerbin 150040; 3.Pathological ward of Hospital affiliated to Heilongjiang University of Traditional Chinese Medicine Haerbin 150040 |
| Abstract: | Objective： To investigate the influences of YITAI Compounded Medication on the contents of Procollagen Ⅲ N - terminal Peptide（PⅢNP）of the model rats with chronic pancreatitis fibrosis. Methods： To establish the chronic pancreatitis rats model with L -arginine with the method of celiac injection, we gave them Y1 TA1 Compounded Medication and collected serum to check the contents of PⅢNP with the method of double antibody sandwich. Results： The contents of PⅢNP in model group was obviously higher than normal group, Chinese medicine control group and Chinese medicine treatment group, the contents of PⅢNP in Chinese medicine treatment group was lower than Chinese medicine control group. Conclusions： Y1TA1 Compounded Medication can decrease the contents of PⅢNP in serum, so it plays an important role in the recovery of chronic pancreatitis fibrosis. |
| Keywords: | Chronic Pancreatitis Fibrous of Chronic YITAI Compounded Medication Pancreatitis Procollagen Ⅲ N - terminal Peptide（PⅢNP） |
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