踝臂指数评价冠心病患者外周动脉疾病的临床研究

目的观察冠状动脉粥样硬化性心脏病（冠心病）患者合并外周动脉疾病（PAD）的发病情况,探讨踝臂指数（ABI）在临床上的应用价值。方法选取冠心病患者269例,收集相关临床资料并检测相关生化指标,采用科林动脉硬化检测仪测量受试者的ABI值。结果冠心病患者中合并PAD者82例,总患病率为30.5%,女性PAD患病率明显高于男性（36.6%比21.0%,P〈0.01）。PAD组年龄、总胆固醇、缺血性脑卒中显著高于非PAD组（P〈0.05或〈0.01）,多因素Logistic回归分析显示,性别、年龄、总胆固醇及缺血性脑卒中是冠心病患者伴PAD的危险因素。结论 ABI是筛查冠心病患者伴PAD的简单易行又可靠的指标,性别、年龄、总胆固醇及缺血性脑卒中是冠心病患者ABI降低的危险因素。

Clinical study on the significance of ankle brachial index in evaluating peripheral artery disease of patients with coronary heart disease

Objective To observe the incidence of the peripheral artery disease（PAD）in patients with coronary heart disease and to explore the clinical application value of ankle brachial index（ABI）.Methods 269 patients with coronary heart disease were enrolled.The clinical data were colleted to detect the biochemical parameters.The value of ABI was measured by oscillometric measurement.The date were analyzed with SPSS 13.0 software.Results Among 269 patients,there were 82 patients with PAD,and the total prevalence of PAD was 30.5%.The prevalence of PAD in males and females were 36.6% and 21.0% respectively,and there was a significant difference between the two genders（P〈0.01）.There were significant differences in the patients＇ age（65.244±11.558 years vs 59.497±9.383 years）,total cholesterol levels（5.484±1.271 mmol/L vs 5.078±1.114 mmol/L）,the incidence of ischemic stroke（19.5% vs 8.6%）between non-PAD group and PAD group（P〈0.05 or P〈0.01）.The logistic regression analysis showed that the patients＇ gender,age,total cholesterol levels and ischemic stroke were major risk factors of PAD in patients with coronary heart disease.Conclusion ABI is a feasible and reliable index for screening PAD in patients with coronary heart disease.The patients gender,age,total cholesterol levels and the incidence of ischemic stroke are major risk factors of ABI decrease in patients with coronary heart disease.