| CD147和MMP-2在早期食管癌中的表达 |
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| 引用本文： | 刘海明,窦俊峰.CD147和MMP-2在早期食管癌中的表达[J].中外医疗,2010,29(29):3-3,5. |
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| 作者姓名： | 刘海明 窦俊峰 |
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| 作者单位： | 河南省卫生学校附属医院,河南安阳,455000 |
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| 摘 要： | 目的探讨CD147和MMP-2在食管癌发生过程中的作用及其相关性。方法应用免疫组织化学S-P法检测CD147和MMP-2在19例食管早期癌和20例正常食管黏膜标本中的表达。结果 CD147和MMP-2在早期癌中的表达均高于正常食管黏膜（P〈0.05）。结论 CD147和MMP-2可能与食管癌的发生有关,他们的变化可能是食管癌发生中的早期事件。
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| 关 键 词： | p21 p16 食管早期癌 免疫组织化学 |
The Expression of CD147 and MMP-2 in Human Early Esophageal Carcinoma |
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| LIU Haiming,DOU Junfeng.The Expression of CD147 and MMP-2 in Human Early Esophageal Carcinoma[J].China Foreign Medical Treatment,2010,29(29):3-3,5. |
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| Authors: | LIU Haiming DOU Junfeng |
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| Institution: | The Affiliated Hospital of Henan Medical School,Henan 455000,China |
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| Abstract: | Objective To study the effect of CD147 and MMP-2 in esophageal carcinogenesis and their relationship.Methods Immunohistochemical S-P method was used to detect the expressions of CD147 and MMP-2 in 19 cases of esophageal early carcinoma and 20 cases of normal esophageal mucous.Results The expression of CD147 and MMP-2 were both higher in early esophageal carcinoma than in normal esophageal mucous（P0.05）.Conclusion CD147 and MMP-2 are probably related to esophageal carcinogenesis,and their changes are early events in esophageal carcinogenesis. |
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| Keywords: | p21 p16 |
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