| 静注 FX530 对移植性兔 VX2 肿瘤血流灌注的实验研究 |
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| 引用本文： | 柳建华!广州市510180,张青萍!武汉市430030,周翔!武汉市430030,周玉清!武汉市430030,黄道中!武汉市430030,乐桂蓉!武汉市430030,黎春蕾!武汉市430030. 静注 FX530 对移植性兔 VX2 肿瘤血流灌注的实验研究[J]. 中华肿瘤防治杂志, 1999, 0(3) |
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| 作者姓名： | 柳建华!广州市510180 张青萍!武汉市430030 周翔!武汉市430030 周玉清!武汉市430030 黄道中!武汉市430030 乐桂蓉!武汉市430030 黎春蕾!武汉市430030 |
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| 作者单位： | 广东省广州市第一人民医院 (柳建华!广州市510180)，同济医科大学附属同济医院超声科 (张青萍!武汉市430030，周翔!武汉市430030，周玉清!武汉市430030，黄道中!武汉市430030，乐桂蓉!武汉市430030)，同济医科大学附属同济医院超声科(黎春蕾!武汉市430030) |
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| 摘 要： | 目的：评价应用新型声学造影剂观察移植性兔 Ｖ Ｘ２ 肿瘤血流灌注的情况。方法：经静脉注射 Ｆ Ｘ５３０ 后，应用二维灰阶图像、彩色多普勒血流成像、彩色多普勒能量图以及瞬间反应成像等技术观察兔肝脏、肾脏以及肌肉内移植性 Ｖ Ｘ２ 肿瘤的血流灌注情况。结果：造影后增强了肝脏、肾脏等组织器官的灰阶图像和肿瘤内小血管的彩色多普勒血流信号，提高了肿瘤的可视性，增加了肿瘤的检出率。结论：经静脉注射新型声学造影剂是观察肿瘤血流灌注的有效方法。
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| 关 键 词： | 新型声学造影剂 超声 VX2肿瘤 灌注 |
Experimental study of FX530 to trahsplanted VX2 tumor perfusion by intravenous injection |
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| Abstract: | Objective:To investigate the efficacy of a new generation of ultrasonographic contrast agent in the evaluation of transplanted VX2 tumor perfusion by intravenous injection.Methods:After intravenous administration of FX530, grey scale sonography, color Doppler flow imaging,color Doppler energy imaging and transient response imaging were used to evaluate the perfusion of VX2 tumors in liver, kidney and muscule in 15 rabbits.Results:After injection,grey scale sonography and the signals of small vessel of the tumors on color Doppler imaging were well enhanced in both liver and kidney parenchyma, the visibility of the VX2 tumors were greatly improved, and therefore,the rate of tumor detection was nereas.Conclusions:Intravenous contrast agent is useful for assessment of tumor perfusion. |
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| Keywords: | ultrasonographic contrast agent ultrasonography VX2 tumor perfusion |
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