心肌梗死后合并室壁瘤形成的相关因素分析

目的:分析心肌梗死(MyocardialInfarction,MI)后室壁瘤形成的相关危险因素。方法:收集513例患者的临床资料,经左心室造影证实有室壁瘤者为室壁瘤组,其余为非室壁瘤组。用单因素和多因素分析比较两组患者间的病史特点、症状和冠脉造影结果。结果:513例MI患者合并室壁瘤形成62例,发生率为12.1%。单因素分析结果显示在年龄、心绞痛病史、心肌梗死病史、前壁心肌梗死、非有效的溶栓或介入治疗、三支病变、无侧支循环、主要血管的完全闭塞或次全闭塞性病变方面,两组比较有显著性差异,P均<0.05。多因素Logistic回归分析显示:前壁心肌梗死、侧支循环、非有效的溶栓或介入治疗、主要血管的完全闭塞或次全闭塞性病变等因素有显著性差异,P均<0.05。结论:前壁心肌梗死、非有效的溶栓或介入治疗、主要血管的完全闭塞或次全闭塞性病变是急性心肌梗死后室壁瘤形成的独立相关因素。

Analysis of the Related Factors for Development of Ventricular Aneurysm After Myocardial Infarction

Objective: To analyze the related risk factors for develpment of ventricular aneurysm(VA) after myocardial infarction(MI). Methods:The clinical data of 513 patients were analyzed. These patients were divided into two groups according to the result of ventricular aneurysm development diagnosed by left ventricular angiography. The patients with ventricular aneurysm entered group VA. The others entered group NVA. Historical features, symptoms,and data of coronary artery angiography(CAG) were compared between two groups by single factor and multifactorial regressin ananlysis. Results:There were 62 patients who developed VA among 513 patients with MI. It's morbidity was 12.1%. It was shown by single factor analysis that there were differences between two groups in respect of age, angina history, MI history, anterior MI, effective or in effective obstructive thrombolytic and interventional therapy, lesions in three-branch, collateral circulation and total or subtotal obstructive lesions in major branch of artery(all P value< 0.005). And it also was shown by multifactorial regressin analysis that there were differences in anterior MI, ineffective therapy by thrombolysis and intervention, and total or subtotal obstractive lesions in major branch artery(all P value< 0.005). Conclusions: The following factors are independent relative factors for VA development: anterior MI, ineffective thrombolysis and interventional therapy, and total or subtotal obstructive lesions in major branch artery.