不育症男性风疹病毒感染与精子DNA碎片率的相关分析 |
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引用本文: | 胡慧敏. 不育症男性风疹病毒感染与精子DNA碎片率的相关分析[J]. 浙江中西医结合杂志, 2020, 30(10) |
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作者姓名: | 胡慧敏 |
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作者单位: | 浙江省中西医结合医院 |
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基金项目: | 杭州市医药卫生科技计划项目(2016A038) |
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摘 要: | 目的:探讨不育症男性风疹病毒(Rubella virus)感染情况及其与精子DNA碎片率的关系。 方法:检测553例不育男性患者血清中的风疹病毒IgM抗体,将患者分为风疹病毒IgM(RV-IgM)阳性组和风疹病毒IgM(RV-IgM)阴性组,分别检测精子DNA碎片率。 结果:RV-IgM阳性组的精子DNA碎片率显著高于RV-IgM阴性组(P<0.05)。结论:风疹病毒急性感染对精子DNA完整性有影响,可能导致男性不育。
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关 键 词: | 男性 不育症 风疹病毒 精子DNA碎片率 |
收稿时间: | 2020-06-29 |
修稿时间: | 2020-07-29 |
The relationship analysis of Rubella virus infection with sperm DNA fragmentation index in male infertility |
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Abstract: | Objective: To investigate status of Rubella virus(RV)infection in male infertility,and analyze the relationship of Rubella virus infection with sperm DNA fragmentation index(DFI).Methods:Detect serum Rubella virus antibody in 553 patients of male infertility.The patients were divided into the positive group of RV-IgM and the negative group of RV-IgM.Then detect their sperm DNA fragmentation index.Results: Sperm DNA fragmentation index in the positive group of RV-IgM were significantly higher than that in the negative group of RV-IgM. Conclusion:Rubella virus recent infection can affect sperm DNA fragmentation index,it may be one reason of male infertility. |
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Keywords: | male infertility Rubella virus infection sperm DNA fragmentation index |
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