| 怀菊花浸膏对自发性高血压大鼠血压及其靶器官脂质过氧化作用的影响 |
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| 引用本文： | 方家选,臧文华. 怀菊花浸膏对自发性高血压大鼠血压及其靶器官脂质过氧化作用的影响[J]. 河南中医学院学报, 2006, 21(5): 18-19 |
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| 作者姓名： | 方家选 臧文华 |
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| 作者单位： | [1]南阳医学专科学校,河南南阳473000 [2]河南中医学院2003级硕士研究生,河南郑州450008 |
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| 摘 要： | 目的:研究怀菊花浸膏对自发性高血压大鼠(SHR)有无降压作用及可能机理.方法:采用自发性高血压大鼠为动物模型,观察高血压大鼠血压及心、脑、肾组织MDA、SOD含量的变化.结果:怀菊花浸膏高剂量组能降低高血压大鼠血压,显著增高心、脑、肾组织SOD水平,降低MDA含量.结论:怀菊花浸膏可能有降压作用和减轻靶器官脂质过氧化损伤作用.
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| 关 键 词： | 怀菊花 高血压 脂质过氧化物 大鼠 |
| 文章编号： | 1672-6839(2006)05-0018-02 |
| 修稿时间： | 2006-06-11 |
Effects of Huai Chrysanthemum Extractum on Blood Pressure and Lipid Peroxidation of Target-organ in Spontaneous Hypertension Rats |
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| Fang Jiaxuan,Zang Wenhua. Effects of Huai Chrysanthemum Extractum on Blood Pressure and Lipid Peroxidation of Target-organ in Spontaneous Hypertension Rats[J]. Journal of Henan University of Chinese Medicine, 2006, 21(5): 18-19 |
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| Authors: | Fang Jiaxuan Zang Wenhua |
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| Abstract: | Objective: To investigate if Huai Chrysanthemum extractum possesses antihypertensive effect in spontaneous hypertension rats (SHR) and its possible mechanism. Methods: Spontaneous hypertension rats (SHR) were used.The change of blood pressure of SHR and the content of superoxide dismutase (SOD), maleic dialdehyde (MDA) in heart, brain and kidney tissue were investigated. Results: Huai Chrysanthemum extractum high-dose group can lower blood pressure of SHR; reduce MDA in heart, brain and kidney tissue; raise the content of SOD in heart, brain and kidney tissue. Conclusion: The result shows that Huai Chrysanthemi extractum can drop the blood pressure of SHR;inhibit lipid peroxidation; protect the target-organ-heart, brain and kidney from hypertension-induced damage. |
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| Keywords: | Huai Chrysanthemi Hypertension Lipid peroxides Rats |
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