甲硝唑联合维生素E治疗老年性阴道炎的临床观察

目的观察甲硝唑片联合维生素E胶囊外用治疗老年性阴道炎的临床效果。方法将120例老年性阴道炎患者随机分为2组,治疗组60例给予甲硝唑片每晚0.2 g阴道上药,同时维生素E胶囊10 mg阴道上药。甲硝唑每月连用7 d停药,维生素E胶囊每日持续阴道上药。连续治疗观察3个月。对照组60例给予替硝唑阴道泡腾片每晚0.2 g阴道上药,每月连用8 d停药,连续治疗观察3个月。结果治疗10 d、4周、3个月后,2组疗效比较均有显著性差异(P均<0.01)。结论甲硝唑配合维生素E胶囊外用治疗老年性阴道炎疗效好,值得推广应用。

Clinic observation of senile vaginitis treatment using Metronidazole tablets combined with vitamin E capsules

Objective It is to observe the clinic effect of Metronidazole tablets combined with Vitamin E capsules(for external use) on senile vaginitis.Methods 120 cases of patients with senile vaginitis were randomly divided into 2 groups: treatment group and control group with 60 cases in each one.The treatment group was given Metronidazole tablets and Vitamin E capsule by vagina drug administration.Metronidazole’s dosage was 0.2 g daily,applied every night for 7 consecutive nights each month,and Vitamin E’s dosage was 10 mg daily,every night.The control group was given Tinidazole effervescent tablet by vagina drug administration,whose dosage was 0.2 g daily,applied every night for 8 consecutive nights each month.The above therapy and observation last for 3 months.Results After 10days’,4 weeks’ and 3 months’ treatment,the curative effects between both groups were significantly different(P all < 0.01).Conclusion The treatment of Senile vaginitis using Metronidazole tablets in combination with Vitamin E capsules(for external use) has good curative effect.