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多发性硬化35例临床分析
引用本文:衣晶,韩燕,邵小秋,骆晓薇,焦洪云,陈俊红. 多发性硬化35例临床分析[J]. 中国神经免疫学和神经病学杂志, 2001, 8(3): 151-152
作者姓名:衣晶  韩燕  邵小秋  骆晓薇  焦洪云  陈俊红
作者单位:1. 北京矿物局总医院神经内科,
2. 北京回民医院神经内科,
3. 北京协和医院神经内科,
摘    要:目的 探讨多发性硬化(MS)的临床特点。方法 综合分析35例MS患者的一般临床资料、病变部位、重要辅助检查及治疗转归。结果 MS多见于青壮年女性,病程多缓解与复发、上呼吸道感染、劳累紧张为其主要诱因,脑脊液显示免疫活性增高,视神经、脊髓受累多见,电生理、免疫学及影像学检查有助诊断,糖皮质激素治疗有效。结论 根据临床特点、综合神经电生理、脑脊液免疫学及影像学检查能明显提高临床确诊率。

关 键 词:多发性硬化 免疫学 诱发电位 磁共振成像
文章编号:1006-2963(2001)03-151-03
修稿时间:2000-08-07

Clinical Analysis of 35 Patients with Multiple Sclerosis
YI Jing ,HAN Yan ,SHAO Xiao qiu ,LUO Xiao wei ,JIAO Hong yun ,CHEN Jun hong. Clinical Analysis of 35 Patients with Multiple Sclerosis[J]. Chinese Journal of Neuroimmunology and Neurology, 2001, 8(3): 151-152
Authors:YI Jing   HAN Yan   SHAO Xiao qiu   LUO Xiao wei   JIAO Hong yun   CHEN Jun hong
Affiliation:YI Jing 1,HAN Yan 2,SHAO Xiao qiu 3,LUO Xiao wei 1,JIAO Hong yun 1,CHEN Jun hong 1
Abstract:Objective To study the clinical features of multiple sclerosis (MS).Methods The general clinical manifestations lesion locations, the results of cardinal ancillary investigations, and treatment as well as prognosis of 35 MS patients were comprehensively analyzed.Results MS was mainly consisted young and middle aged women. Their onsets were relatively acute. The alleviation and recurrence of the disease happened alternately during the course.The upper respiratory tract infection and tire out were the main inducements.The immunocompetence of CSF was increased. Optic nerves and spinal cord were often involved. Electrophysiology, immunology and imaging investigations were helpful to diagnosis. The administrationofglucocorticoidwas effective.Conclusions In addition to clinical features,neuroelectrophysiology,CSF immunology and imaging investigations altogether aid greatly clinical definite diagnosis.
Keywords:multiple sclerosis  immunology  evoked potential  MRI  
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