| THE BLOCKING EFFECTS OF GLYCYRRHIZE URALENSIS AND CHELIDONIUM MAJUS ON MUTAGENESIS INDUCED BY AFLATOXIN B1 |
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| 引用本文： | 史桂芝,纪新华,梁益新,陈小琦.THE BLOCKING EFFECTS OF GLYCYRRHIZE URALENSIS AND CHELIDONIUM MAJUS ON MUTAGENESIS INDUCED BY AFLATOXIN B1[J].中国癌症研究,1994(2). |
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| 作者姓名： | 史桂芝 纪新华 梁益新 陈小琦 |
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| 作者单位： | Department of Cancer Etiology，Beijing Institute for Cancer，Beijing 100034 |
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| 摘 要： | ＴＨＥＢＬＯＣＫＩＮＧＥＦＦＥＣＴＳＯＦＧＬＹＣＹＲＲＨＩＺＥＵＲＡＬＥＮＳＩＳＡＮＤＣＨＥＬＩＤＯＮＩＵＭＭＡＪＵＳＯＮＭＵＴＡＧＥＮＥＳＩＳＩＮＤＵＣＥＤＢＹＡＦＬＡＴＯＸＩＮＢ１ＳｈｉＧｕｉｚｎｉ；史桂芝；ＪｉＸｉｎｈｕａ；纪新华；ＬｉａｎｇＹ...
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THE BLOCKING EFFECTS OF GLYCYRRHIZE URALENSIS AND CHELIDONIUM MAJUS ON MUTAGENESIS INDUCED BY AFLATOXIN B1 |
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| Shi Guizni, Ji Xinhua, Liang Yixin, Chen Xiaoqi,.THE BLOCKING EFFECTS OF GLYCYRRHIZE URALENSIS AND CHELIDONIUM MAJUS ON MUTAGENESIS INDUCED BY AFLATOXIN B1[J].Chinese Journal of Cancer Research,1994(2). |
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| Authors: | Shi Guizni Ji Xinhua Liang Yixin Chen Xiaoqi |
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| Abstract: | Glycyrrhiza Uralensis(GU) and Chelidoniuni Majus (CM) (25,50,100, 200 mg/plate) have obvious blocking effects on Salmonella Typhimurium strains (TA97,TA98,TA100, TA102) mutagenesis induced by aflatoxim B1 (AFB1). The blocking rates of GU and CM are more dependent on the doses. A compound of GU and CM, called Wei Lingsu (WLS), could impede chromosomol aperrations and sister chromatid exchanges (SCE) of human peripheral lymphocyte induced by AFB1, at the concentrations of 150 mg/ml, the blocking rates are 52. 94% 88. 24% and 15. 50% 38. 23% saperatly. WLS could also impede the inhibition of AFB1 to lymphocyte mitosis. |
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| Keywords: | Glycyrrhiza Uralensis(GU) Chelidonnium Majus(CM) Blockinhg effects Mutagenesis |
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