中药发酵的现代研究进展与展望

发酵作为常用的中药炮制技术之一,是指在一定条件下,借助微生物和酶的催化分解作用,改变原有药性、药效的方法.在此基础上,通过与微生物技术的融合又发展出现代发酵技术,因微生物在发酵过程中发挥出强大的生物转化能力,并能产生丰富的次生代谢产物,具有一般炮制方法所无法比拟的优势,进而成为中药研究的热点之一.文章系统综述了中药发酵...

Progress and prospect of modern research on fermented Chinese materia medica

The fermentation of Chinese materia medica is a traditional Chinese medicine processing method, which refers to the properties and pharmacological activities of Chinese materia medica can be changed by microorganisms and enzymes under certain circumstances. Based on this, modern fermentation technology is developed with the help of microbial technology. In the process of fermentation, organisms show brilliant biotransformation ability, and can produce a wealth of secondary metabolites, which is more advantageous than general processing methods and has become a hot spot of current research. In this study, we summarized fermentation methods, strains, analysis technologies of fermentation system and effects on chemical constituent, property and flavor, pharmacological activity. This study will be hoped to provide ideas and references for the further development and applications of fermentation technology of Chinese materia medica.