肠易激综合征患者睡眠功能障碍分析及其与精神和胃肠道症状的相关性

目的 分析肠易激综合征(IBS)患者睡眠功能,并分析睡眠功能与精神、胃肠道症状的相关性,以期为IBS患者的临床诊疗提供参考。 方法 分析2015年1月-2017年1月在宁波市医疗中心李惠利医院接受诊疗的肠易激综合征患者的临床资料,并列为观察组。另纳入同期行健康体检的患者作为对照组。共纳入观察组45例,对照组40例。睡眠状况评估采用匹斯堡睡眠质量指数(PSQI),胃肠道症状采用IBS症状严重程度量表(IBS-SSS)评估,精神症状分别采用汉密尔顿焦虑量表(HAMA)及汉密顿抑郁量表(HAMD)评估。 结果 观察组患者PSQI评分显著高于对照组(9.21±2.50 vs. 5.38±0.45;t=9.547,P<0.01)。观察组PSQI>7分的比例为80%(36/45)。观察组患者IBS-SSS评分为(195.8±39.7)分,HAMD评分为(19.2±3.6)分,HAMA评分为(21.5±4.1)分。相关性分析显示,观察组患者PSQI与IBS-SSS评分(r=0.820,P<0.01)、HAMD评分(r=0.617,P<0.01)及HAMA评分(r=0.697,P<0.01)之间存在显著正相关关系。 结论 睡眠功能障碍在IBS患者中较为普遍,且睡眠功能障碍的程度与患者精神及胃肠道症状程度密切相关。 

Analyze the sleep dysfunction for patients with irritable bowel syndrome and its correlation with psychiatric and gastrointestinal symptom

Objective To analyze the sleep dysfunction for patients with irritable bowel syndrome (IBS) and its correlation with psychiatric and gastrointestinal symptom. Methods Clinical data of patients with IBS received treatment at our hospital from 2015 to 2017 were analyzed as Group A. Healthy cases were enrolled as Group B. Pittsburgh sleep quality index (PSQI), IBS symptom severity scale (IBS-SSS), Hamilton anxiety scale (HAMA) and Hamilton depression scale (HAMD) were evaluated and analyzed. Results A total of 85 patients were analyzed, Group A 45 cases, Group B 40 cases. Group A patients had higher PSQI scores than that of Group B (9.21±2.50 vs. 5.38±0.45; t=9.547, P<0.01). The Group A patients's IBS-SSS scores was 195.8±39.7, HAMD scores was 19.2±3.6 and HAMA scores was 21.5±4.1. Correlation analysis showed that, for Group A patients, the PSQI scores had significant positive correlation with IBS-SSS (r=0.820, P<0.01), HAMD (r=0.617, P<0.01) and HAMA (r=0.697, P<0.01). Conclusion IBS patients were early suffered from sleep dysfunction and which was associated with psychiatric and gastrointestinal symptom.