多发性骨髓瘤的免疫基因治疗 |
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引用本文: | 秋玉珍. 多发性骨髓瘤的免疫基因治疗[J]. 昆明医科大学学报, 2016, 37(6) |
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作者姓名: | 秋玉珍 |
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作者单位: | (昆明医科大学第二附属医院血液科,云南 昆明 650101) |
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基金项目: | [基金项目]国家自然科学基金资助项目(81160074) |
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摘 要: | [摘要]多发性骨髓瘤(multiple myeloma,MM)是一种恶性浆细胞单克隆增生性疾病,约占全部恶性肿瘤的1%,目前仍不能治愈,微小残留病是主要原因,因此,清除微小残留病,有可能治愈本病.在各种治疗方法中,针对多发性骨髓瘤的免疫基因疗法(Immune gene therapy 或 Immunogene therapy)是当今治疗的研究热点,近几年免疫基因疗法在体内外实验中取得了较好的结果,本文就免疫基因在多发性骨髓瘤治疗中的研究及应用进行综述.
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关 键 词: | [关键词]多发性骨髓瘤 免疫疗法 基因疗法 |
The Research Progress of Immune Gene Therapy on the Treatment of Multiple myeloma |
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Affiliation: | (Dept.of Hematology,The 2st Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650101,China) |
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Abstract: | [Abstract]Multiple myeloma (MM) is a malignant plasma cell disease, accounting for about 1% of all malignant tumors, is still uncurable, minimal residual disease(MRD) is the reason, therefore,removal of minimal residual disease maybe possible to cure the disease. In a variety of treatment methods, immune gene therapy for multiple myeloma is a hot research topic in recent years, has achieved good results in vitro and in vivo experiments, in this review immune genes therapy in multiple myeloma research would be discussed. |
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