不同性角色男男性行为人群的肛周人乳头瘤病毒感染及影响因素分析

目的 了解不同性角色男男性行为人群（men who have sex with men，MSM）的肛周人乳头瘤病毒（human papillomavirus，HPV）感染状况及其相关危险因素。方法 2016年3月~2017年4月于乌鲁木齐市采用滚雪球抽样法招募MSM 704名，通过问卷调查收集人口学与性行为特征数据，采集肛管内脱落细胞并使用37型HPV检测试剂盒进行分型鉴定。结果 MSM的肛周HPV既往感染率为50.4%，其中性角色"0"组与性角色"1"组的肛周HPV总感染率和低危型HPV的感染率不同，分别为54.6%、18.8%与45.6%、11.9%，差异均有统计学意义（均有P<0.05）。多因素Logistic回归分析显示，肛交有时使用安全套、近6个月同性商业性行为是性角色"0"组感染HPV的危险因素（均有P<0.05）；近6个月同性商业性行为是性角色"1"组感染HPV的危险因素（OR=3.04，95%CI:1.21~7.62，P=0.018）。结论 性角色"0"组与性角色"1"组之间肛周HPV感染率有差异，结合危险因素提倡MSM督促性伴使用安全套、避免商业性行为。

Analysis of anal human papillomavirus infection and influencing factors among different sex role of men who have sex with men

Objective To understand the Human Papillomavirus(HPV) infection status among different sex role of men who have sex with men(MSM) and to analyze relevant risk factors. Methods A total of 704 MSM were recruited by using the"snowballing"sampling method from March 2016 to April 2017 in Urumqi. Data on the demographic and sexual behavioral characteristics of MSM were collected by questionnaires. The cells in anal canal were collected and the 37-type HPV test kits were used for identification and classification. Results The previous anal HPV infection rate of MSM was 50.4%, of which the overall and low-risk HPV infection rate in "0" sex role group and "1" sex role group was different, namely, 54.6%,18.8% and 45.6%, 11.9% respectively, and the difference was statistically significant (all P<0.05). Multiple Logistic regression analysis showed that sometimes using condoms when having anal sex and homosexual commercial sex in nearly six months was the risk factor for HPV infection in "0" sex role group(all P<0.05), while having homosexual commercial sex in nearly six months was the risk factor for HPV infection in "1" sex role group(OR=3.04,95% CI:1.21-7.62, P=0.018). Conclusions The anal HPV infection rate between "0" sex role group and "1" sex role group was different. In view of risk factors, MSM should urge sexual partners adhere to using condoms and avoid commercial sex.