| 肿瘤坏死因子拮抗剂在治疗非银屑病性皮肤病中的临床应用 |
| |
| 引用本文： | 罗玲玲,崔盘根. 肿瘤坏死因子拮抗剂在治疗非银屑病性皮肤病中的临床应用[J]. 中国麻风皮肤病杂志, 2018, 34(11): 698 |
| |
| 作者姓名： | 罗玲玲 崔盘根 |
| |
| 作者单位： | 中国医学科学院北京协和医学院皮肤病医院，江苏南京，210042 |
| |
| 摘 要： | 肿瘤坏死因子拮抗剂通过阻断肿瘤坏死因子与其受体的结合而阻止胞内信号的传递、下游炎症因子的激活及细胞增殖而达到抗炎作用。用于临床的肿瘤坏死因子拮抗剂主要包括英夫利昔单抗（IFX）、依那西普( ENT)、阿达木单抗( ADA)等，在皮肤科中已广泛应用于非银屑病的治疗，本文对其进行了综述。
|
| 关 键 词： | 肿瘤坏死因子 拮抗剂 非银屑病性皮肤病 |
Update of tumor necrosis factor inhibitor for the treatment of non-psoriatic skin diseases |
| |
| LUO Lingling,CUI Pangen. Update of tumor necrosis factor inhibitor for the treatment of non-psoriatic skin diseases[J]. China Journal of Leprosy and Skin Diseases, 2018, 34(11): 698 |
| |
| Authors: | LUO Lingling CUI Pangen |
| |
| Affiliation: | Institute of Dermatology,Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042, China |
| |
| Abstract: | Inhibition of tumor necrosis factor (TNF) plays an important role in anti-inflammation through blocking the binding of TNF and receptors to suppressing the activation of inflammatory factors, transmission of intracellular signals and cell proliferation. The common TNF inhibitors including infliximab (IFX), etanercept (ENT) and adalimumab (ADA) have widely being used in the treatment of non-psoriatic skin diseases, which is reviewed in this paper. |
| |
| Keywords: | tumor necrosis factor inhibitor skin diseases besides psoriasis |
|
| 点击此处可从《中国麻风皮肤病杂志》浏览原始摘要信息 |
|
点击此处可从《中国麻风皮肤病杂志》下载免费的PDF全文 |
