乌鲁木齐市500例2型糖尿病患者抑郁症患病状况及其影响因素研究

目的 探讨乌鲁木齐市2型糖尿病患者合并抑郁症状况及其影响因素。方法 采用横断面调查，对2016年12月1日~2017年4月30日在新疆医科大学第五附属医院内分泌科门诊就诊及住院部确诊的糖尿病患者开展问卷调查。采用Zung氏抑郁自评量表评价患者抑郁症患病情况。采用Logistic回归模型分析糖尿病发生抑郁症的影响因素。结果 500例糖尿病患者，其抑郁症患病率为20.00%，多元Logistic回归分析后结果显示:女性（与男性比较，OR=2.18，95%CI:1.49~3.19），维吾尔族（与汉族比较，OR=2.56，95%CI:1.17~5.57），离异/丧偶（与已婚比较，OR=1.74，95%CI:1.04~3.07）是糖尿病合并抑郁症的独立危险因素；大学文化程度及以上（与小学文化程度及以下比较，OR=0.38，95%CI:0.19~0.76），有家庭支持（与无家庭支持比较，OR=0.50，95%CI:0.28~0.91）是糖尿病合并抑郁症的保护因素。结论 乌鲁木齐市糖尿病患者中抑郁症患病率较高，且与多种因素相关，诊疗时应及早筛查，及时干预，改善患者生活质量。

Prevalence and predictors of depression in 500 diabetic patients in the city of Urumqi

Objective To investigate the prevalence and predictors of depression among patients with diabetes mellitus in Wulumuqi, China. Methods A cross-sectional survey was conducted among patients diagnosed with diabetes in outpatient clinics and inpatients from December 1st, 2016 to April 30th, 2017 in Xinjiang Medical University the Fifth Affiliated Hospital. The depression status was screened using Zung's Self-Rating Depression Scale. Logistic regression model was used to analyze the predictors of depression among diabetic patients. Results The prevalence of depression was 20.00% in 500 patients with diabetes mellitus. The results of logistic regression analysis showed that female (compared to male, OR=2.18, 95% CI:1.49-3.19) and Uyghur (compared to Han ethnic group, OR=2.56,95% CI:1.17-5.57) divorced or widowed (compared to being married, OR=1.74,95% CI:1.04-3.07) were independent risk factors of depression. Education level equal to or higher than college (compared to primary school and lower, OR=0.38, 95% CI:0.19-0.76), family support(Yes/No, OR=0.50,95% CI:0.28-0.91) were protective factors for depression. Conclusions The prevalence of depression in patients with diabetes in Urumqi city is high, and it is related to multiple factors. Early diagnosis and intervention on depression in diabetic patients are recommended to improve the quality of life of diabetic patients.