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CT灌注成像对脾脏疾病诊断的应用价值
作者姓名:孙立辉
作者单位:(1)深圳市龙岗区第二人民医院放射科,广东 深圳 518112;2)昆明医科大学第二附属医院放射科,云南 昆明 650101)
基金项目:[基金项目]深圳市医疗卫生非扶持类项目(YLWSF20150512142013012)
摘    要:[摘要]目的 探讨CT灌注成像对脾脏疾病诊断的应用价值.方法 选取深圳市龙岗区第二人民医院2012年1月至2014年12月收治的脾脏疾病患者20例,将其作为A组,其中,脾脏淋巴瘤患者有7例,作为A1组,白血病脾浸润患者有8例,作为A2组,脾脏转移瘤患者有5例,作为A3组.同时选取20例健康体检者作为对照组,作为B组.结果 B组经CT扫描均正常,A组患者经CT扫描脾脏实质出现各种病变.A组患者脾脏灌注量与对照组相比明显升高且差异有统计学意义(P<0.05).与CT平扫相比,CT灌注成像检出率明显升高且差异有统计学意义(P<0.05).A组各患者TIP、MTT与B组相比均明显升高,BF、PEI、BV均明显降低且差异有统计学意义(P<0.05).结论 CT灌注成像创伤较小,对脾脏疾病诊断价值较高,是临床较为理想的检测方法,可以进行应用推广.

关 键 词:[关键词]CT灌注成像    脾脏疾病诊断    应用价值

Applied Research of CT Perfusion Imaging on the Diagnosis of Splenic Diseases
Institution:(1)Dept. of Radoilogy,The No.2 People’s Hospital of Long-gang District Shenzhen,Shenzhen Guangdong 518112;2)Dept. of Radoilogy,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650101,China)
Abstract:[Abstract]Objective To discuss the applied research of CT perfusion imaging on the diagnosis of splenic diseases. Methods 20 patients with splenic diseases which accepted treatment in our hospital from January 2012 to December 2014 were assigned into group A, including 7 cases of splenic lymphoma patients(group A1), 8 cases of leukemia patients with spleen infiltration (group A2) and 5 cases of splenic metastasis(group A3). At the same time, 20 healthy persons were selected as the control (group B). Results The result of CT scan was normal in group B, but that showed a variety of lesions in the spleen in group A. The spleen perfusion volume in the group A was significantly higher than that in the control group (P<0.05). The detection rate of CT perfusion imaging was significantly higher than that of CT scan (P<0.05). TIP and MTT in group A were significantly higher than those in group B,while BF, PEI and BV were significantly lower (P<0.05). Conclusion CT perfusion imaging has advantage of simple, short imaging time,less trauma,and a high diagnostic value for the spleen disease, which is an ideal detection means and can be used in clinic.
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