303例药疹临床分析

目的:明确我院303例药疹患者的致敏药物。方法 对2006年9月至2016年8月间303例药疹患者的临床资料进行回顾性分析。结果：303例药疹患者中，重症药疹34例，轻中度药疹269例，其中188例患者为发疹型药疹。183例轻中度药疹患者可明确致敏药物，主要致敏药物为抗生素144例，解热镇痛药致敏22例。31例重症药疹患者可明确致敏药物，主要致敏药物为抗癫痫药物11例，抗痛风药物8例，抗生素7例。结论：本院轻中度药疹患者中抗生素类为最常见的致敏药物，重症药疹中抗癫痫药为最常见的致敏药物。

Clinic analysis of 303 cases with drug eruption

Objective: To determine the allergenic drugs in 303 inpatients with drug eruption in our hospital. Methods: The data of 303 patients with drug eruption, diagnosed from September 2006 to August 2016, was analyzed retrospectively. Results: Out of 303 patients, there were 34 patients with severe drug eruption and 269 patients with mild-moderate drug eruptions. Out Of the 269 patients with mild-moderate drug eruptions, exanthematous?type (188 patients) was the most. The allergenic drugs in 183 patients with mild-moderate drug eruption mainly included antibiotics in 144 patients and analgesic-antipyretic in 22. The allergenic drugs in 31 patients with sever drug eruption mainly included antiepileptic drugs in 11 patients, anti-gout?drugs in 8 and antibiotics in another 7. Conclusion: The most common allergenic drugs in the patients with mild-moderate drug eruption were antibiotics and the most common allergenic drugs in the patients with sever drug eruption were antiepileptic drugs.