清腺汤治疗小儿腺样体肥大痰瘀互结型26例临床观察

目的观察清腺汤治疗小儿腺样体肥大痰瘀互结型的临床疗效。方法选取2017年10月至2018年9月湖州市中医院儿科就诊的腺样体肥大痰瘀互结型患儿52例,按随机数字表法分为治疗组和对照组,各26例。治疗组口服清腺汤,对照组口服孟鲁斯特钠,2组均4周为1个疗程,1个疗程后统计疗效。结果治疗组总有效率为88.46%(23/26),显著高于对照组的30.77%(8/26),2组比较,差异有统计学意义(P<0.05)。治疗前,2组中医证候积分比较,差异无统计学意义(P>0.05),具有可比性;治疗后,2组中医证候积分均较同组治疗前减少,且治疗组减少更显著,差异均有统计学意义(P<0.05)。治疗前,2组腺样体与鼻咽腔气道厚度比值(A/N)比较,差异无统计学意义(P>0.05),具有可比性;治疗后,2组A/N均较同组治疗前降低,且治疗组降低更显著,差异均有统计学意义(P<0.05)。结论清腺汤治疗小儿腺样体肥大痰瘀互结型疗效显著,能显著改善患儿的症状和体征,值得临床推广应用。

Clinical observation on 26 cases of adenoidal hypertrophy in children with phlegm accumulating with stagnation type treated by Qingxian Tang(清腺汤)

Objective To observe the clinical efficacy of Qingxian Tang(清腺汤)in the treatment of adenoidal hypertrophy in children with phlegm accumulating with stagnation type.Methods Fifty-two cases of adenoidal hypertrophy in children with phlegm accumulating with stagnation type consulted in pediatrics department of Huzhou Hospital of TCM from October 2017 to September 2018 were divided into treatment group and control group according to random number table method,with 26 cases in each.The treatment group was given oral Qingxian Tang,while the control group was given oral montelukast sodium.Four weeks constituted 1 course of treatment for both groups.We kept statistics about the efficacy after 1 course.Results The total effective rate of the treatment group was 88.46%(23/26),which was significantly higher than 30.78%(8/26)of the control group,and the difference between the 2 groups was statistically significant(P<0.05).Before treatment,the difference was not statistically significant in TCM symptom scores between the 2 groups(P>0.05),and they were comparable.After treatment,TCM symptom scores of the 2 groups decreased compared with the same group before treatment,moreover,the treatment group decreased more significantly,and the difference was statistically significant(P<0.05).Before treatment,the difference was not statistically significant in ratio of thickness of adenoid to nasopharyngeal airway(A/N)value between the 2 groups(P>0.05),and they were comparable.After treatment,A/N value of the 2 groups decreased compared with the same group before treatment,moreover,the treatment group decreased more significantly,and the difference was statistically significant(P<0.05).Conclusion It has marked efficacy to use Qingxian Tang in the treatment of adenoidal hypertrophy in children with phlegm accumulating with stagnation type,which can markedly improve symptoms and signs and deserves clinical promotion and application.