家庭被动吸烟和挑食与学龄前儿童多动行为的交互作用

目的 以学龄前儿童为调查对象,探讨家庭被动吸烟和挑食及其交互作用对学龄前儿童多动行为的影响。 方法 2014年5月-2015年6月,采用自行设计问卷对马鞍山市91所幼儿园3~6岁儿童家长进行问卷调查,共计收回15 291份有效问卷。调查儿童一般人口学特征、被动吸烟和挑食行为,用Conners简明症状问卷评估儿童多动行为,总分≥ 15分为存在多动行为。采用Logistic回归模型分析被动吸烟和挑食对学龄前儿童多动行为的相乘交互作用,采用相对超额危险度比评估相加交互作用。 结果 实际调查15 291名学龄前儿童,筛查出多动行为儿童1 317人,总检出率为8.6%。家庭被动吸烟和挑食与儿童多动行为之间均存在正相关[OR=1.24(1.10~1.39),P<0.001;OR=2.11(1.88~2.37),P<0.001]。分层研究显示,无论是否存在被动吸烟,儿童挑食均与多动行为有统计学关联[OR=2.60(2.19~3.10),P<0.001;OR=1.79(1.53~2.09),P<0.001]。不挑食的儿童,家庭被动吸烟与多动行为有关[OR=1.45(1.24~1.69),P<0.001]。家庭被动吸烟和挑食对多动行为存在相乘交互作用[(OR=0.69(0.54~0.87),P<0.01],但是不存在相加交互作用(RERI=0.60,95%CI=-0.14~1.34)。 结论 家庭被动吸烟和挑食与学龄前儿童多动行为之间存在关联,同时存在相乘交互作用,但是无相加交互作用。 

Interaction of household passive smoking with pickiness on hyperactivity behavior among preschool children

Objective To explore the interaction between household passive smoking and pickiness on hyperactivity behavior in preschool children. Methods A total of 15 291 parents of preschool children from 91 kindergartens were investigated by self-designed questionnaire from May, 2014 to June, 2015. A "Conners abbreviated symptom questionnaire" was used to rate hyperactivity behavior. The multivariate logistic regression and the relative excess risk due to interaction (RERI) were performed to assess the interaction of household passive smoking with pickiness on hyperactivity behavior. Results In our study, the detection rate of hyperactivity behavior was 8.6%. The household passive smoking and pickiness were significantly associated with hyperactivity behavior[OR=1.24(1.10-1.39), P<0.001; OR=2.11(1.88-2.37), P<0.001]. The results of stratified analysis showed that household passive smoking was related with hyperactivity behavior in the children without pickiness[OR=1.45(1.24-1.69), P<0.001]; but whether or not with household passive smoking, the pickiness was associated with hyperactivity behavior[OR=2.60(2.19-3.10), P<0.001; OR=1.79(1.53-2.09), P<0.001]. The multiplicative interaction of household passive smoking and pickiness on hyperactivity behavior was statistically significant[OR=0.69(0.54-0.87), P<0.01], but the additive interaction was not (RERI=0.60, 95%CI=-0.14-1.34). Conclusion The household passive smoking and pickiness were significantly associated with hyperactivity behavior and had a multiplicative interaction on hyperactivity behavior.