乳腺癌改良根治术与Ⅰ期重建术后生活质量的对比分析

  目的   比较改良根治手术和乳房Ⅰ期重建手术对中国女性乳腺癌患者生活质量和满意度的影响。   方法   入选2011年7月至2013年7月间在中国医学科学院肿瘤医院接受手术治疗的乳腺癌患者60例，其中改良根治术组30例，乳房Ⅰ期重建组30例，分别给予乳腺癌患者生命质量测定量表（FACT-B）和自制量表。   结果   两组间基本资料、乳腺癌病理及切口愈合情况差异均无统计学意义（P > 0.05），具有良好的匹配性。与改良根治术组相比，乳房Ⅰ期重建组患者具有较好的外形满意度（33.2±8.8 vs. 41.1±10.8，P=0.003）。但两组间FACT-B评分和心理影响评分差异无统计学意义（P > 0.05）。   结论   乳房Ⅰ期重建组患者外形满意度明显优于改良根治组。 

Quality of life among Chinese women with breast cancer after modified radical mastectomy and immediate breast reconstruction: A comparative study

  Objective   This study was conducted to evaluate whether or not immediate breast reconstruction influences quality of life and patient body image satisfaction outcomes among Chinese women with breast cancer compared with modified radical mastectomy.   Methods   Sixty patients with breast cancer and were operated from July 2011 to July 2012 in Cancer Institute & Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College were included. These patients were divided into two groups: Ⅰ (30 patients) underwent modified radical mastectomy and Ⅱ (30 patients) underwent mastectomy with immediate breast reconstruction. Patient satisfaction with breast reconstruction was evaluated by functionally assessing cancer therapy-breast cancer scale (FACT-B) and the scales that we designed.   Results   No significant differences were observed between the two groups in terms of baseline characteristics, histopathological characteristics, and incision conditions (P > 0.05). The patients in groupⅡ (immediate breast reconstruction) exhibited improved body image satisfaction outcomes (41.1 ± 10.8 vs. 33.2 ± 8.8, P=0.003); this difference was still observed after adjustment for confounding factors was performed by multiple linear regression. No significant difference was found between the two groups in terms of total FACT-B score and psychological evaluation score (P > 0.05).   Conclusions   Chinese women who prefer immediate breast reconstruction exhibited an improved body image satisfaction.